Early Echographic Asystole as a Predictive Factor of Absence of Spontaneous Circulatory Activity Recovery (SCAR) in Prehospital Cardio Respiratory Arrests (CRA) (ACE)

NCT03494153 COMPLETED

Assessment of prognostic performances of CCU in CRA Recovery (CRAR) has already been explored but 1) Only in intra-hospital medicine, 2) in very variable timings. ACE Research focuses on the extra-hospital window and predictive value of Early CCU (within 12 minutes of rescucitation initiation) with ambitious endpoints : curable etiologies identification, early anticipation of ECMO procedures, early anticipation of organ donation process, and evaluation of intrinsic contribution criterion to resuscitation interruption. The primary objective of ACE study is to investigate the positive predictive value (PPV) of early ultrasound asystole on the absence of CRAR. The secondary objectives are multiple and innovative despite an observational design: impact on the morbi-mortality of the target population (frequency of curable etiologies, pre-therapeutic and therapeutic delays, morbidity...), delay of ECMO implementation of an ECMO (Extracorporeal Membrane Oxygenation), failure rate of organ donation due to overdelays, construction of a multifactorial score associated with CRAR.

Details

Lead sponsor	Nantes University Hospital
Status	COMPLETED
Enrolment	346
Start date	Wed Jan 23 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Jan 23 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Prehospital Cardio-Respiratory Arrests
• Spontaneous Circulatory Activity Recovery

Interventions

• Non applicable - Non interventional study

Countries

France