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NCT03490461
Effects of Statin on Hepatocellular Carcinoma Recurrence After Liver Transplantation
trial testing Statin in Hepatocellular Carcinoma in 350 participants. Completed in 1 March 2018.
1 March 2018
Quick facts
| Lead sponsor | Yonsei University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 350 |
| Start date | 22 November 2017 |
| Primary completion | 1 March 2018 |
| Estimated completion | 1 March 2018 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Statin — full drug profile →
Conditions studied
- Hepatocellular Carcinoma — all drugs for Hepatocellular Carcinoma →
Sponsor
Yonsei University
Who can join
Adults 20 to 80, any sex, with Hepatocellular Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate whether statin therapy can help prevent recurrence of hepatocellular carcinoma (HCC) in transplant recipients who had liver transplantation for HCC. Multiple logistic regression analysis will be performed to evaluate the association between statin therapy and the risk of HCC recurrence after LT.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Metabolic reprogramming in the tumor microenvironment of liver cancer.
Lin J, Rao D, Zhang M, Gao Q. · · 2024 · cited 117× · PMID 38297372 · DOI 10.1186/s13045-024-01527-8 -
The role of metabolic reprogramming in liver cancer and its clinical perspectives.
Lu M, Wu Y, Xia M, Zhang Y. · · 2024 · cited 16× · PMID 39610917 · DOI 10.3389/fonc.2024.1454161 -
Potential Molecular Targeted Therapy for Unresectable Hepatocellular Carcinoma.
Kumar S, Pandey AK. · · 2023 · cited 3× · PMID 36826066 · DOI 10.3390/curroncol30020105 -
Metabolic Crossroad Between Macrophages and Cancer Cells: Overview of Hepatocellular Carcinoma.
Santarsiero A, Convertini P, Iacobazzi D, Infantino V, et al · · 2024 · cited 1× · PMID 39767591 · DOI 10.3390/biomedicines12122684
Verify or expand the search:
- PubMed search for NCT03490461
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06553157 — Statins Effect on Incidence of Side Effects of Platinum Based Chemotherapy · Phase 1, PHASE2 · completed
- NCT06520904 — Effect of PCSK9 Inhibitors on Coronary Atherosclerotic Plaques Derived From Optical Coherence Tomography · Phase 4 · recruiting
Other recruiting trials for Hepatocellular Carcinoma
Currently open trials in the same condition.
- NCT06902246 — Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma · Phase 2 · recruiting
- NCT05842174 — Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma · Phase 1, PHASE2 · recruiting
- NCT07417397 — Adjuvant TACE in HCC With High-risk Recurrence Factors · Phase 3 · recruiting
- NCT07317414 — β-alanine in the Treatment of Advanced Hepatocellular Carcinoma · Phase 2 · recruiting
- NCT07148050 — Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimer · Phase 1 · recruiting
Other Yonsei University trials
Trials by the same sponsor.
- NCT07547592 — Gemcitabine and Docetaxel With or Without Bevacizumab (Onbevzi) for Soft Tissue Sarcoma · Phase 2 · not yet recruiting
- NCT07524101 — Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD · NA · not yet recruiting
- NCT07506629 — Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty · NA · not yet recruiting
- NCT07515716 — Effects of High Flow Humidified Oxygen on Umbilical Artery Acid-base Balance in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
- NCT07507188 — Collaborative Clinical-translational Cohort of Amivantamab Plus Lazertinib and Amivantamab Plus Chemotherapy in Patients · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03490461 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yonsei University
- Last refreshed: 6 April 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03490461.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing