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NCT03487302
White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study
trial testing Brain MRI in Aging, Premature in 146 participants. Completed in 31 December 2021.
31 December 2021
Quick facts
| Lead sponsor | IRCCS Policlinico S. Donato |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 146 |
| Start date | 17 October 2017 |
| Primary completion | 31 December 2021 |
| Estimated completion | 31 December 2021 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Brain MRI — full drug profile →
- Neuropsychological test battery
Conditions studied
- Aging, Premature — all drugs for Aging, Premature →
- Congenital Heart Disease — all drugs for Congenital Heart Disease →
- White Matter Hyperintensities — all drugs for White Matter Hyperintensities →
Sponsor
IRCCS Policlinico S. Donato
Who can join
20 and older, any sex, with Aging, Premature or Congenital Heart Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aims at investigating the role of cyanotic congenital heart disease (cCHD) on brain aging. The investigators assume that due to congenital and acquired cardiovascular abnormalities, cCHD patients could show radiologic (and clinical) signs of precocious brain aging and eventual cognitive decline.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03487302
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Aging, Premature
Currently open trials in the same condition.
- NCT05838560 — Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders · Phase 2 · active not recruiting
Other IRCCS Policlinico S. Donato trials
Trials by the same sponsor.
- NCT07295522 — Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? · Phase 4 · not yet recruiting
- NCT07169669 — Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syndrome · not yet recruiting
- NCT07455292 — Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging · NA · recruiting
- NCT07402161 — The Signature of Alzheimer's Disease in Subjective Cognitive Decline · recruiting
- NCT06294119 — Multivariate Approach to the Numerical Assessment of Cortical - Autonomic - VAscular Dynamic Interplay · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03487302 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS Policlinico S. Donato
- Last refreshed: 13 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03487302.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing