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NCT03487185: SLEEP
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy
NA trial testing Continuous Positive Airway Pressure in Obstructive Sleep Apnea of Adult in 1,500 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | The George Washington University Biostatistics Center |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 1,500 |
| Start date | 3 August 2018 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 14 locations across United States |
Drugs / interventions tested
- Continuous Positive Airway Pressure
- Sleep Advice Control
Conditions studied
- Obstructive Sleep Apnea of Adult — all drugs for Obstructive Sleep Apnea of Adult →
- Preeclampsia — all drugs for Preeclampsia →
- Obstetrical Complications — all drugs for Obstetrical Complications →
Sponsor
The George Washington University Biostatistics Center
Who can join
18 and older, female only, with Obstructive Sleep Apnea of Adult or Preeclampsia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Associations Between Sleep Disorders and Hypertensive Disorders of Pregnancy and Materno-fetal Consequences.
Querejeta Roca G, Anyaso J, Redline S, Bello NA. · · 2020 · cited 14× · PMID 32671579 · DOI 10.1007/s11906-020-01066-w -
Obstructive sleep apnea in pregnant women.
Dominguez JE, Habib AS. · · 2022 · cited 5× · PMID 35261345 · DOI 10.1097/aia.0000000000000360
Verify or expand the search:
- PubMed search for NCT03487185
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Continuous Positive Airway Pressure
Trials testing the same drug.
- NCT07247318 — The Effects of Different Non-invasive Respiratory Support · NA · not yet recruiting
- NCT06795971 — Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intub · NA · recruiting
- NCT06512779 — Developing a Treatment Clustering System for Obstructive Sleep Apnea Using Polysomnographic Physiological Signals · NA · recruiting
- NCT06391138 — The Effect of OSA on Pregnancy and Fetal Outcomes · not yet recruiting
- NCT06393023 — The Effect of OSA on Severity and Prognosis of Patients With CKD · not yet recruiting
Other recruiting trials for Obstructive Sleep Apnea of Adult
Currently open trials in the same condition.
- NCT06792188 — Smartwatch-Based AI Model for OSA Prediction (SWOSA) · recruiting
- NCT06512779 — Developing a Treatment Clustering System for Obstructive Sleep Apnea Using Polysomnographic Physiological Signals · NA · recruiting
- NCT06117579 — Effect of Inspiratory Muscle Training in Obstructive Sleep Apnea Syndrome. · NA · recruiting
- NCT06447818 — Changes in Difficult Airway Markers After Surgery for Obstructive Sleep Apnoea Syndrome · recruiting
- NCT06103630 — Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device · NA · recruiting
Other The George Washington University Biostatistics Center trials
Trials by the same sponsor.
- NCT06980025 — Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial · Phase 3 · recruiting
- NCT06605118 — Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial · Phase 3 · recruiting
- NCT04296396 — Opioid Prescription After Cesarean Trial · Phase 3 · completed
- NCT04519502 — Maternal Morbidity and Mortality During the COVID-19 Pandemic · completed
- NCT03944512 — Pravastatin to Prevent Preeclampsia · Phase 3 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03487185 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The George Washington University Biostatistics Center
- Last refreshed: 6 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03487185.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing