NCT03482284 (ENDO-META) is a NA clinical trial of Dietary Intervention in Dietary Habits, sponsored by Prof. Dr. Ina Bergheim.

Who is sponsoring NCT03482284?

NCT03482284 is sponsored by Prof. Dr. Ina Bergheim.

What drugs are being tested in NCT03482284?

Interventions in NCT03482284: Dietary Intervention.

What condition does NCT03482284 study?

NCT03482284 studies Dietary Habits, Endotoxemia.

Is NCT03482284 still recruiting?

NCT03482284 is currently completed. Last updated 17 April 2019.

Last reviewed 2019-04-17 · How we verify

NCT03482284: ENDO-META

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Monosaccharides on Intestinal Barrier Function

Completed NA Last updated 17 April 2019

What this trial tests

NA trial testing Dietary Intervention in Dietary Habits in 12 participants. Completed in 1 August 2018.

Timeline

20 May 2016

Primary endpoint
9 September 2017

1 August 2018

Quick facts

Lead sponsor	Prof. Dr. Ina Bergheim
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	none
Primary purpose	basic science
Enrollment	12
Start date	20 May 2016
Primary completion	9 September 2017
Estimated completion	1 August 2018

Drugs / interventions tested

Dietary Intervention

Conditions studied

Dietary Habits — all drugs for Dietary Habits →
Endotoxemia — all drugs for Endotoxemia →

Sponsor

Prof. Dr. Ina Bergheim

Who can join

Adults 18 to 75, any sex, with Dietary Habits or Endotoxemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the present study is to determine the effect of monosaccharides on intestinal barrier function in healthy subjects.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Short-Term Isocaloric Intake of a Fructose- but not Glucose-Rich Diet Affects Bacterial Endotoxin Concentrations and Markers of Metabolic Health in Normal Weight Healthy Subjects.
Nier A, Brandt A, Rajcic D, Bruns T, et al · · 2019 · cited 36× · PMID 30570214 · DOI 10.1002/mnfr.201800868
Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and 'inflammaging'.
Brandt A, Baumann A, Hernández-Arriaga A, Jung F, et al · · 2022 · cited 32× · PMID 36356464 · DOI 10.1016/j.redox.2022.102528
Toll-like receptor 1 as a possible target in non-alcoholic fatty liver disease.
Baumann A, Nier A, Hernández-Arriaga A, Brandt A, et al · · 2021 · cited 24× · PMID 34497333 · DOI 10.1038/s41598-021-97346-9
Alcohol Use and Abuse Conspires With HIV Infection to Aggravate Intestinal Dysbiosis and Increase Microbial Translocation in People Living With HIV: A Review.
Yan J, Ouyang J, Isnard S, Zhou X, et al · · 2021 · cited 11× · PMID 34975838 · DOI 10.3389/fimmu.2021.741658
Fructose intake enhances lipoteichoic acid-mediated immune response in monocytes of healthy humans.
Staltner R, Csarmann K, Geyer A, Nier A, et al · · 2025 · cited 1× · PMID 40517600 · DOI 10.1016/j.redox.2025.103729

Verify or expand the search:

Other trials of Dietary Intervention

Trials testing the same drug.

NCT06391099 — Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic · NA · recruiting
NCT07091864 — Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma · NA · recruiting
NCT06954584 — Fluzoparib+Bevacizumab/Dietary Intervention vs Fluzoparib Monotherapy as First-line Maintenance in HRD+/- Advanced Ovari · Phase 3 · recruiting
NCT06900439 — Exploring Glycemic Responses Through Continuous Monitoring in a Healthy Population · NA · completed
NCT06336902 — Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients With KRAS-Mutant Metastatic Colorec · Phase 1 · recruiting

Other recruiting trials for Dietary Habits

Currently open trials in the same condition.

NCT07385820 — A Comparative Intervention Study on Strategies for Fruit Distribution and Awareness Campaigns in Schools · NA · recruiting
NCT07027865 — Sip and Snack Better (SSB) Study: Improving Added Sugar in Adolescents · NA · active not recruiting
NCT07411677 — My Life - I Decide: A Health Promoting School Intervention · NA · active not recruiting
NCT05862818 — Can Food Timing Reduce Your Diabetes Risk? · NA · recruiting
NCT06912425 — Effects of an Exercise and Diet Program on Biochemistry and Body Composition in Patients With CKD in G1 and G2 Stages · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03482284 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Prof. Dr. Ina Bergheim
Last refreshed: 17 April 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03482284.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing