Who is sponsoring NCT03481140?

NCT03481140 is sponsored by Cohera Medical, Inc..

What drugs are being tested in NCT03481140?

Interventions in NCT03481140: TissuGlu Surgical Adhesive.

What condition does NCT03481140 study?

NCT03481140 studies Deep Inferior Epigastric Perforator Flap Reconstruction.

Is NCT03481140 still recruiting?

NCT03481140 is currently completed. Last updated 29 March 2018.

Last reviewed 2018-03-29 · How we verify

NCT03481140

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Case Series Comparing Drains to TissuGlu® in a Donor Site DIEP Flap Breast Reconstruction Procedure

Completed Last updated 29 March 2018

What this trial tests

trial testing TissuGlu Surgical Adhesive in Deep Inferior Epigastric Perforator Flap Reconstruction in 58 participants. Completed in 30 November 2017.

Timeline

21 April 2015

Primary endpoint
30 November 2017

30 November 2017

Quick facts

Lead sponsor	Cohera Medical, Inc.
Status	Completed
Study type	OBSERVATIONAL
Enrollment	58
Start date	21 April 2015
Primary completion	30 November 2017
Estimated completion	30 November 2017

Drugs / interventions tested

TissuGlu Surgical Adhesive

Conditions studied

Deep Inferior Epigastric Perforator Flap Reconstruction — all drugs for Deep Inferior Epigastric Perforator Flap Reconstruction →

Sponsor

Cohera Medical, Inc.

Who can join

18 and older, any sex, with Deep Inferior Epigastric Perforator Flap Reconstruction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate the safety and effectiveness of a lysine-derived urethane adhesive (TissuGlu® Surgical Adhesive) as a less invasive alternative to surgical drains in the abdominal donor site for deep inferior epigastric perforator (DIEP) flap reconstruction.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Three-Dimensional Disassemblable Scaffolds for Breast Reconstruction.
Kiseleva V, Bagdasarian A, Vishnyakova P, Elchaninov A, et al · · 2025 · PMID 40808084 · DOI 10.3390/polym17152036

Verify or expand the search:

Other trials of TissuGlu Surgical Adhesive

Trials testing the same drug.

NCT03482999 — Case Series Assessing TissuGlu® Surgical Adhesive in Flap Surgery for Decubitus Repair · completed

Other Cohera Medical, Inc. trials

Trials by the same sponsor.

NCT02960139 — A Clinical Study Comparing Standard Anastomosis Closure Technique to Standard Closure Technique Plus Sylys® Surgical Sea · NA · terminated
NCT03482999 — Case Series Assessing TissuGlu® Surgical Adhesive in Flap Surgery for Decubitus Repair · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03481140 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cohera Medical, Inc.
Last refreshed: 29 March 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03481140.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing