NCT03479879 is a Phase 2, PHASE3 clinical trial of Estradiol in Miscarriage, sponsored by Ain Shams University.

Who is sponsoring NCT03479879?

NCT03479879 is sponsored by Ain Shams University.

What drugs are being tested in NCT03479879?

Interventions in NCT03479879: Estradiol, Placebo Oral Tablet, Misoprostol.

What condition does NCT03479879 study?

NCT03479879 studies Miscarriage.

Is NCT03479879 still recruiting?

NCT03479879 is currently completed. Last updated 29 January 2019.

Last reviewed 2019-01-29 · How we verify

NCT03479879

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Estradiol Pretreatment With Misoprostol in Second Trimester Miscarriage

Completed Phase 2, PHASE3 Last updated 29 January 2019

What this trial tests

Phase 2, PHASE3 trial testing Estradiol in Miscarriage in 200 participants. Completed in 20 December 2018.

Timeline

21 March 2018

Primary endpoint
20 December 2018

20 December 2018

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 2, PHASE3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	200
Start date	21 March 2018
Primary completion	20 December 2018
Estimated completion	20 December 2018
Sites	1 location across Egypt

Drugs / interventions tested

Estradiol (ESTRADIOL) — full drug profile →
Placebo Oral Tablet — full drug profile →
Misoprostol (Misoprostol) — full drug profile →

Conditions studied

Miscarriage — all drugs for Miscarriage →

Sponsor

Ain Shams University

Who can join

Adults 18 to 40, female only, with Miscarriage. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To compare the effectiveness of estradiol pretreatment with misoprostol and vaginal misoprostol alone in induction of second trimestr miscarriage.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Estradiol

Trials testing the same drug.

NCT05457972 — Postpartum Vaginal Estrogen for Breastfeeding Patients · Phase 4 · recruiting
NCT06253702 — Brain Blood Flow Responses to Stress: Sex Differences · Phase 4 · completed
NCT06005610 — Estradiol Therapy In Transgender Women to Research Interactions With HIV Therapy · Phase 2 · terminated
NCT05617820 — Study Comparing Estradiol Vaginal Inserts 4mcg To IMVEXXY ® (Estradiol Vaginal Inerts 4 mcg) In The Treatment Of Dyspare · Phase 3 · completed
NCT06116201 — Influences of Long Term Hormone Therapy on Physical Fitness and Vascular Function in Transgender Women · NA · completed

Other recruiting trials for Miscarriage

Currently open trials in the same condition.

NCT07109947 — Use of Aromatase Inhibitor Before Misoprostol in Medical Termination of Miscarriage · NA · recruiting
NCT06576622 — PERIodontal Disease, Microbiota and Miscarriage · recruiting
NCT06862089 — A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMV · recruiting
NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
NCT05725512 — Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages · Phase 4 · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03479879 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 29 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03479879.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing