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NCT03479723
Identification of Predictors for Coronary Plaque Erosion in Patients With Acute Coronary Syndrome
trial in Acute Coronary Syndrome in 1,793 participants. Completed in 1 August 2024.
1 December 2019
Quick facts
| Lead sponsor | Massachusetts General Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,793 |
| Start date | 1 December 2017 |
| Primary completion | 1 December 2019 |
| Estimated completion | 1 August 2024 |
| Sites | 1 location across United States |
Conditions studied
- Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →
Sponsor
Massachusetts General Hospital
Who can join
18 and older, any sex, with Acute Coronary Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to perform pooled analysis with data collected from 5 previously published studies and 8 unpublished datasets collected from international sites. The main goal of this study is to identify the predictors of plaque erosion.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
Calcified Plaques in Patients With Acute Coronary Syndromes.
Sugiyama T, Yamamoto E, Fracassi F, Lee H, et al · · 2019 · cited 110× · PMID 30898249 · DOI 10.1016/j.jcin.2018.12.013 -
Clinical and Laboratory Predictors for Plaque Erosion in Patients With Acute Coronary Syndromes.
Yamamoto E, Yonetsu T, Kakuta T, Soeda T, et al · · 2019 · cited 83× · PMID 31640466 · DOI 10.1161/jaha.119.012322 -
Sex Differences in Culprit Plaque Characteristics Among Different Age Groups in Patients With Acute Coronary Syndromes.
Seegers LM, Araki M, Nakajima A, Yonetsu T, et al · · 2022 · cited 42× · PMID 35652353 · DOI 10.1161/circinterventions.121.011612 -
Seasonal Variations in the Pathogenesis of Acute Coronary Syndromes.
Kurihara O, Takano M, Yamamoto E, Yonetsu T, et al · · 2020 · cited 21× · PMID 32611221 · DOI 10.1161/jaha.119.015579 -
Coronary Plaque Characteristics and Underlying Mechanism of Acute Coronary Syndromes in Different Age Groups of Patients With Diabetes.
Suzuki K, Niida T, Yuki H, Kinoshita D, et al · · 2023 · cited 13× · PMID 38014673 · DOI 10.1161/jaha.123.031474 -
Age and Phenotype of Patients With Plaque Erosion.
Araki M, Yonetsu T, Kurihara O, Nakajima A, et al · · 2021 · cited 12× · PMID 34569250 · DOI 10.1161/jaha.120.020691 -
Cardiovascular Risk Factors and Culprit Plaque Characteristics in Women With Acute Coronary Syndromes.
Seegers LM, Yeh DD, Wood MJ, Yonetsu T, et al · · 2023 · cited 8× · PMID 37722196 · DOI 10.1016/j.amjcard.2023.08.152 -
Layered plaque and plaque volume in patients with acute coronary syndromes.
Yuki H, Kinoshita D, Suzuki K, Niida T, et al · · 2023 · cited 7× · PMID 36869878 · DOI 10.1007/s11239-023-02788-9
Verify or expand the search:
- PubMed search for NCT03479723
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Massachusetts General Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03479723 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
- Last refreshed: 29 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03479723.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing