NCT03476629: PAH

Effects of Different Types of Physical Training in Patients With Pulmonary Arterial Hypertension.

Status unknown NA Last updated 4 November 2020

What this trial tests

NA trial testing Physical activity in Pulmonary Arterial Hypertension in 45 participants. Status unknown.

Timeline

10 January 2016

Primary endpoint
10 July 2017

10 December 2020

Quick facts

Lead sponsor	University of Nove de Julho
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	treatment
Enrollment	45
Start date	10 January 2016
Primary completion	10 July 2017
Estimated completion	10 December 2020
Sites	1 location across Brazil

Drugs / interventions tested

• Physical activity

Conditions studied

• Pulmonary Arterial Hypertension — all drugs for Pulmonary Arterial Hypertension →
• Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
• Respiratory Disease — all drugs for Respiratory Disease →
• Hypertension, Pulmonary — all drugs for Hypertension, Pulmonary →

Sponsor

University of Nove de Julho

Who can join

Adults 20 to 70, any sex, with Pulmonary Arterial Hypertension or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Although there has been some progress in pharmacological management of PAH, limited functional capacity and low survival still persist, but there is evidence that exercise training can be accomplished without adverse effects or damage to cardiac function and pulmonary hemodynamics. Specifically, improvements in symptoms, exercise capacity, peripheral muscle function and quality of life. Training programs need to be better studied and well defined, and their physiological effects during physical training and functional capacity.

The aim of this study is to compare the effects of different training exercises on physical performance indicators.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Exercise-based rehabilitation programmes for pulmonary hypertension.
   Morris NR, Kermeen FD, Jones AW, Lee JY, et al · · 2023 · cited 29× · PMID 36947725 · DOI 10.1002/14651858.cd011285.pub3