Who is sponsoring NCT03475797?

NCT03475797 is sponsored by Nantes University Hospital.

What drugs are being tested in NCT03475797?

Interventions in NCT03475797: Occipital nerve stimulation, Optimal Medical Management.

What condition does NCT03475797 study?

NCT03475797 studies Occipital Neuralgia.

Is NCT03475797 still recruiting?

NCT03475797 is currently terminated. Last updated 11 October 2021.

Last reviewed 2021-10-11 · How we verify

NCT03475797: StimO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of Occipital Nerve Stimulation in Intractable Occipital Neuralgias

Terminated NA Last updated 11 October 2021

What this trial tests

NA trial testing Occipital nerve stimulation in Occipital Neuralgia in 22 participants. Terminated before completion.

Timeline

20 April 2018

Primary endpoint
26 June 2021

3 September 2021

Quick facts

Lead sponsor	Nantes University Hospital
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	22
Start date	20 April 2018
Primary completion	26 June 2021
Estimated completion	3 September 2021
Sites	10 locations across France

Drugs / interventions tested

Occipital nerve stimulation
Optimal Medical Management

Conditions studied

Occipital Neuralgia — all drugs for Occipital Neuralgia →

Sponsor

Nantes University Hospital

Who can join

Adults 18 to 85, any sex, with Occipital Neuralgia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Medically intractable pain caused by occipital neuralgia can be very difficult to control with traditional pain management. Peripheral nerve stimulation which is used in migraines and cluster headache can be an alternative for these patients with occipital neuralgias when medical treatment and traditional pain management have failed (drugs for neuropathic pain, infiltrations, psychobehavioral approaches and multidisciplinary approach in a pain center). Occipital nerve stimulation consists to put a lead subcutaneously in front of the occipital nerve and to connect the lead to a pulse generator. A retrospective study of 60 patients was conducted in Nantes University Hospital. The results were good with the Visual Analog Scale (VAS) decreased from 8.4 preoperatively to 2.85 postoperatively. The medical quantification scale (MQS) was reduced to about 50% (18 preoperatively versus 9.9 postoperatively). Stimulation was quiet stable over time with a mean follow-up of 24 months (range 6 to 72 months). The aim of StimO is to confirm this result through a national controlled randomized multicenter study where occipital nerve stimulation will be compared to the optimal medical management.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Occipital Nerve Stimulation for Refractory Occipital Neuralgia: A Multicenter, Randomized, Controlled Trial [StimO Study]
Ravaillault S, Alipour H, Leger F, Labarre J, et al · · 2026
Occipital Nerve Stimulation for Refractory Occipital Neuralgia: A Multicenter, Randomized, Controlled Trial [StimO Study].
Ravaillault S, Alipour H, Leger F, Labarre J, et al · · 2026 · PMID 41827338 · DOI 10.3390/jcm15051922

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03475797 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nantes University Hospital
Last refreshed: 11 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03475797.

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