Effective Pain Management During Shoulder Replacement Surgery With EXPAREL

NCT03474510 PHASE4 WITHDRAWN

The purpose of this study is to examine the effectiveness of post-operative pain control of local infiltration (LIA) of EXPAREL administration to ropivacaine administered via continuous interscalene nerve block (CINB) for postoperative pain relief following shoulder replacement. Effectiveness will be measured in opioid consumption and NRS pain intensity scores from 0-4h, 4-8h, 9-12h, 13-16h, 17-20, 21-24h, 48 hours and 72 hours post-op. Patient satisfaction with pain control; patient functional outcome; adverse events related to CINB, EXPAREL administration, and opioid consumption; and pain intensity scores from the time of surgery until post-operative day 10 (+/- 5 days) will also be examined.

Details

Lead sponsor	TriHealth Inc.
Phase	PHASE4
Status	WITHDRAWN
Start date	Sat Mar 17 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Feb 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Pain, Postoperative
• Shoulder Osteoarthritis

Interventions

• local infiltration of liposomal bupivacaine
• continuous infusion of ropivacaine interscalene nerve block

Countries

United States