Who is sponsoring NCT03466502?

NCT03466502 is sponsored by University of Nevada, Reno.

What drugs are being tested in NCT03466502?

Interventions in NCT03466502: Oral Vancomycin.

What condition does NCT03466502 study?

NCT03466502 studies Clostridium Difficile Infection.

Is NCT03466502 still recruiting?

NCT03466502 is currently completed. Last updated 28 November 2023.

Last reviewed 2023-11-28 · How we verify

NCT03466502

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Oral Vancomycin to Prevent Recurrent C Difficile Infection With Antibiotics

Completed Phase 4 Last updated 28 November 2023

What this trial tests

Phase 4 trial testing Oral Vancomycin in Clostridium Difficile Infection in 104 participants. Completed in 17 February 2022.

Timeline

8 March 2018

Primary endpoint
17 February 2022

17 February 2022

Quick facts

Lead sponsor	University of Nevada, Reno
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	104
Start date	8 March 2018
Primary completion	17 February 2022
Estimated completion	17 February 2022
Sites	1 location across United States

Drugs / interventions tested

Oral Vancomycin

Conditions studied

Clostridium Difficile Infection — all drugs for Clostridium Difficile Infection →

Sponsor

University of Nevada, Reno

Who can join

18 and older, any sex, with Clostridium Difficile Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will assess the efficacy of oral vancomycin prophylaxis in preventing recurrent Clostridium difficile infection in hospitalized patients requiring oral or intravenous antibiotics for a suspected or confirmed bacterial infection.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Oral Vancomycin Prophylaxis for Primary and Secondary Prevention of <i>Clostridioides difficile</i> Infection in Patients Treated with Systemic Antibiotic Therapy: A Systematic Review, Meta-Analysis and Trial Sequential Analysis.
Maraolo AE, Mazzitelli M, Zappulo E, Scotto R, et al · · 2022 · cited 24× · PMID 35203786 · DOI 10.3390/antibiotics11020183

Verify or expand the search:

Other trials of Oral Vancomycin

Trials testing the same drug.

NCT07207434 — Maternal Probiotic Intervention to Improve Gut Health-Trial II-Pakistan · Phase 2 · recruiting
NCT07134790 — Maternal Probiotic Intervention to Improve Gut Health - Trial II - Burkina Faso (MPIGH-II) · Phase 2 · recruiting
NCT03617445 — Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients · Phase 2 · terminated
NCT05320068 — Oral Vancomycin Vs Placebo in the Prevention of Recurrence of Clostridioides Difficile's Infection · Phase 3 · completed
NCT05376228 — A Systems Biology Approach for Identification of Host and Microbial Mechanisms and Druggable Targets for the Treatment o · unknown

Other recruiting trials for Clostridium Difficile Infection

Currently open trials in the same condition.

NCT07221370 — Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill Patients · Phase 2, PHASE3 · recruiting
NCT06703918 — Study on Clostridium Difficile Infection in Infants · recruiting
NCT04305769 — Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT) · Phase 2 · recruiting
NCT04014413 — Safety and Efficacy of Fecal Microbiota Transplantation · NA · recruiting
NCT03562741 — Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile · NA · recruiting

Other University of Nevada, Reno trials

Trials by the same sponsor.

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NCT06727786 — Serious Game to Teach Opioid Overdose Response · Phase 2 · not yet recruiting
NCT03328455 — The Role of GABA-mediated Inhibition in Multisensory Temporal Processing & Postural Control in Older Adults · NA · not yet recruiting
NCT06163599 — Reducing Mental Health Disparities Among Latinxs With a Telenovela Intervention · NA · recruiting
NCT05918887 — Feasibility and Acceptability of Switching to E-cigarettes Among Cigarette Smokers Engaged in SUD Treatment · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03466502 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Nevada, Reno
Last refreshed: 28 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03466502.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing