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NCT03465683
Transmission of ESBL-producing Enterobacteriaceae
trial testing ESBL-producing Enterobacteriaceae in Hospital Acquired Infection in 2,000 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | University Hospital, Basel, Switzerland |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 2,000 |
| Start date | 1 March 2017 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- ESBL-producing Enterobacteriaceae
Conditions studied
- Hospital Acquired Infection — all drugs for Hospital Acquired Infection →
Sponsor
University Hospital, Basel, Switzerland
Who can join
1 and older, any sex, with Hospital Acquired Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this research project is to investigate the transmission of ESBL-producing Enterobacteriaceae on both, the level of bacterial strains and mobile genetic elements, and to determine the source of hospital-acquired infections.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Within-host genetic diversity of extended-spectrum beta-lactamase-producing Enterobacterales in long-term colonized patients.
Aguilar-Bultet L, García-Martín AB, Vock I, Maurer Pekerman L, et al · · 2023 · cited 11× · PMID 38129423 · DOI 10.1038/s41467-023-44285-w -
Spatiotemporal dissemination of ESBL-producing Enterobacterales in municipal sewer systems: a prospective, longitudinal study in the city of Basel, Switzerland.
Gómez-Sanz E, Bagutti C, Roth JA, Alt Hug M, et al · · 2023 · cited 10× · PMID 37250050 · DOI 10.3389/fmicb.2023.1174336 -
Extended-spectrum β-lactamase-producing Enterobacterales in diverse foodstuffs: a prospective, longitudinal study in the city of Basel, Switzerland.
Gómez-Sanz E, Bagutti C, García-Martín AB, Roth JA, et al · · 2023 · cited 6× · PMID 38075908 · DOI 10.3389/fmicb.2023.1295037 -
Identification of a Cluster of Extended-spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Sequence Type 101 Isolated From Food and Humans.
Aguilar-Bultet L, Bagutti C, Egli A, Alt M, et al · · 2021 · cited 3× · PMID 32776135 · DOI 10.1093/cid/ciaa1164
Verify or expand the search:
- PubMed search for NCT03465683
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03465683 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Basel, Switzerland
- Last refreshed: 17 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03465683.
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