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NCT03465683

Transmission of ESBL-producing Enterobacteriaceae

Recruiting now Last updated 17 November 2025
What this trial tests

trial testing ESBL-producing Enterobacteriaceae in Hospital Acquired Infection in 2,000 participants. Currently enrolling.

Timeline
1 March 2017
Primary endpoint
31 December 2026
31 December 2026

Quick facts

Lead sponsorUniversity Hospital, Basel, Switzerland
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment2,000
Start date1 March 2017
Primary completion31 December 2026
Estimated completion31 December 2026
Sites1 location across Switzerland

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Basel, Switzerland

Who can join

1 and older, any sex, with Hospital Acquired Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this research project is to investigate the transmission of ESBL-producing Enterobacteriaceae on both, the level of bacterial strains and mobile genetic elements, and to determine the source of hospital-acquired infections.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Within-host genetic diversity of extended-spectrum beta-lactamase-producing Enterobacterales in long-term colonized patients.
    Aguilar-Bultet L, García-Martín AB, Vock I, Maurer Pekerman L, et al · · 2023 · cited 11× · PMID 38129423 · DOI 10.1038/s41467-023-44285-w
  2. Spatiotemporal dissemination of ESBL-producing Enterobacterales in municipal sewer systems: a prospective, longitudinal study in the city of Basel, Switzerland.
    Gómez-Sanz E, Bagutti C, Roth JA, Alt Hug M, et al · · 2023 · cited 10× · PMID 37250050 · DOI 10.3389/fmicb.2023.1174336
  3. Extended-spectrum β-lactamase-producing Enterobacterales in diverse foodstuffs: a prospective, longitudinal study in the city of Basel, Switzerland.
    Gómez-Sanz E, Bagutti C, García-Martín AB, Roth JA, et al · · 2023 · cited 6× · PMID 38075908 · DOI 10.3389/fmicb.2023.1295037
  4. Identification of a Cluster of Extended-spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Sequence Type 101 Isolated From Food and Humans.
    Aguilar-Bultet L, Bagutti C, Egli A, Alt M, et al · · 2021 · cited 3× · PMID 32776135 · DOI 10.1093/cid/ciaa1164

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Trials by the same sponsor.

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Data sources for this page

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