NCT03461705 (RFR) is a NA clinical trial of Volcano Verrata Pressure Wire in Coronary; Ischemic, sponsored by Columbia University.

Who is sponsoring NCT03461705?

NCT03461705 is sponsored by Columbia University.

What drugs are being tested in NCT03461705?

Interventions in NCT03461705: Volcano Verrata Pressure Wire, St. Jude Medical (SJM) Aeris Pressure Wire System.

What condition does NCT03461705 study?

NCT03461705 studies Coronary; Ischemic.

Is NCT03461705 still recruiting?

NCT03461705 is currently terminated. Last updated 7 February 2020.

Are results published for NCT03461705?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2020-02-07 · How we verify

NCT03461705: RFR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Novel Adenosine-independent Index of Coronary Artery Stenosis Severity Resting Flow Reserve

Terminated NA Results posted Last updated 7 February 2020

What this trial tests

NA trial testing Volcano Verrata Pressure Wire in Coronary; Ischemic in 5 participants. Terminated before completion.

Timeline

20 October 2017

Primary endpoint
2 August 2018

2 August 2018

Quick facts

Lead sponsor	Columbia University
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	5
Start date	20 October 2017
Primary completion	2 August 2018
Estimated completion	2 August 2018
Sites	1 location across United States

Drugs / interventions tested

Volcano Verrata Pressure Wire
St. Jude Medical (SJM) Aeris Pressure Wire System

Conditions studied

Coronary; Ischemic — all drugs for Coronary; Ischemic →

Sponsor

Columbia University

Who can join

18 and older, any sex, with Coronary; Ischemic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will enroll patients who are referred for coronary angiography and require physiological assessment to see if the lesion can be treated as per the local standard of care. Approximately 92 participants will be enrolled. There are no follow up visits required so participation in this study will end when subjects are discharged from the hospital.The study will be comparing the resting flow reserve against the instantaneous wave-free ratio (iFR) and fractional flow reserve. All these tests offer a way to image a legion and determine if it is suitable to be treated. FFR measures the pressure differences across (narrowed coronary arteries usually due to atherosclerosis), iFR's are performed during cardiac catheterisation (angiography) using invasive coronary pressure wires which are placed in the arteries of the heart that are to be assessed and the Resting flow reserve looks at the maximum increase in blood flow through the coronary arteries above the normal resting volume.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Coronary; Ischemic

Currently open trials in the same condition.

NCT05868902 — A Registry of Cardiac PET and CardioFlux Magnetocardiography in Patients With Suspected Coronary Ischemia. · recruiting
NCT04674449 — iCorMicA - Stratified Medicine in Angina · NA · recruiting
NCT04827316 — Clinical Utility and Outcome Prediction of Cardiovascular Computed Tomography (PREDICT-CT) · recruiting

Other Columbia University trials

Trials by the same sponsor.

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NCT07264582 — HIV/STI/HCV Testing and Overdose Prevention Among Survivors of Sex Trafficking · NA · not yet recruiting
NCT05992415 — Know Your Pressures NYC · NA · not yet recruiting
NCT05645211 — The AgRP and GH/IGF-1 Axis in Children · not yet recruiting
NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03461705 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Columbia University
Last refreshed: 7 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03461705.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing