Who is sponsoring NCT03461510?

NCT03461510 is sponsored by Nemours Children's Clinic.

What drugs are being tested in NCT03461510?

Interventions in NCT03461510: Hyperglycemic clamp, Hyperinsulinemic Euglycemic clamp.

What condition does NCT03461510 study?

NCT03461510 studies Type 2 Diabetes Mellitus, Obesity, Pediatric Obesity, Insulin Resistance, Dysglycemia, Hyperglycemia.

Is NCT03461510 still recruiting?

NCT03461510 is currently completed. Last updated 9 September 2019.

Last reviewed 2019-09-09 · How we verify

NCT03461510

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Type 2 Diabetes and the Brain in Adolescents

Completed NA Last updated 9 September 2019

What this trial tests

NA trial testing Hyperglycemic clamp in Type 2 Diabetes Mellitus in 18 participants. Completed in 30 January 2019.

Timeline

5 December 2017

Primary endpoint
30 January 2019

30 January 2019

Quick facts

Lead sponsor	Nemours Children's Clinic
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	diagnostic
Enrollment	18
Start date	5 December 2017
Primary completion	30 January 2019
Estimated completion	30 January 2019
Sites	1 location across United States

Drugs / interventions tested

Hyperglycemic clamp — full drug profile →
Hyperinsulinemic Euglycemic clamp — full drug profile →

Conditions studied

Type 2 Diabetes Mellitus — all drugs for Type 2 Diabetes Mellitus →
Obesity — all drugs for Obesity →
Pediatric Obesity — all drugs for Pediatric Obesity →
Insulin Resistance — all drugs for Insulin Resistance →

Sponsor

Nemours Children's Clinic

Who can join

Adults 12 to 18, any sex, with Type 2 Diabetes Mellitus or Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study evaluates differences in brain function and cognitive performance in adolescents with type 2 diabetes (T2D) compared to non diabetic controls (both obese and lean) and correlates these changes with obesity, insulin resistance, and glycemic control in youth with T2D.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Hyperglycemic clamp

Trials testing the same drug.

NCT06727071 — Using Wearable Sensors To Understand Low Blood Sugar in Type 1 Diabetes · NA · not yet recruiting
NCT05499702 — The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction · Phase 2 · recruiting

Other recruiting trials for Type 2 Diabetes Mellitus

Currently open trials in the same condition.

NCT07351058 — A Clinical Study to Evaluate the Effects of RO7795068 in Participants With Obesity or Overweight and Type 2 Diabetes · Phase 3 · recruiting
NCT07373938 — Carotid Wall Texture as a Cardiovascular Risk Biomarker in Type 2 Diabetes Mellitus · recruiting
NCT07433062 — A Study to Evaluate the Effect of AZD6793 on the Pharmacokinetics and Pharmacodynamics of Metformin in Participants With · Phase 1 · recruiting
NCT07276776 — An Evaluation of the Omnipod® M System in Adults With Type 2 Diabetes · NA · active not recruiting
NCT07232537 — An Observational Study Called FINE-REAL Korea to Learn More About the Use of the Drug Finerenone in People With Chronic · recruiting

Other Nemours Children's Clinic trials

Trials by the same sponsor.

NCT06616818 — DASH Diet Intervention for Systemic Hypertension in Adolescents · NA · withdrawn
NCT07218588 — Sanctuary Farm Prescription in Adolescents · NA · recruiting
NCT06406621 — Pilot Trial Assessing the Effectiveness of Laser Hair Depilation on Pilonidal Disease Recurrence in Patients With Darker · NA · recruiting
NCT07154667 — Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction · NA · recruiting
NCT07212049 — Ultrasound Use to Measure Magnetically Controlled Growing Rods · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03461510 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nemours Children's Clinic
Last refreshed: 9 September 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03461510.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing