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NCT03460951: PIDC

Diffusion Tensor Imaging in Chronic Inflammatory Demyelinating Polyneuropathy (PIDC)

Completed Last updated 9 March 2018
What this trial tests

trial testing cervical MRI in CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy) in 45 participants. Completed in 31 December 2015.

Timeline
18 November 2013
Primary endpoint
31 December 2015
31 December 2015

Quick facts

Lead sponsorUniversity Hospital, Clermont-Ferrand
StatusCompleted
Study typeOBSERVATIONAL
Enrollment45
Start date18 November 2013
Primary completion31 December 2015
Estimated completion31 December 2015
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Clermont-Ferrand

Who can join

18 and older, any sex, with CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy) or CMT (Charcot Marie Tooth Disease). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main purpose of this study is to assess the clinical feasibility of diffusion tensor imaging (DTI) for the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). For thar purpose, investigator will compare, fractional anisotropy (FA) obtained by diffusion tensor imaging (DTI) MRI 3T on brachial plexus and cervical spinal nerve roots between patients with defined Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP), according to the EFNS 2010 criteria, and healthy controls. The secondary outcomes will be to compare DTI parameters (FA, ADC or Apparent Diffusion Coefficient) between CIDP patients, healthy volunteers, and patients with Charcot Marie Tooth disease type 1a (CMT1a) and MRI morphological parameters (T1, STIR) between these groups. Moreover, investigator will investigate the possible relationship between MRI parameters, clinical indices, and electrophysiological measure.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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