NCT03457974 is a NA clinical trial of saliva in Cardiac Disease, sponsored by Istanbul University.

Who is sponsoring NCT03457974?

NCT03457974 is sponsored by Istanbul University.

What drugs are being tested in NCT03457974?

Interventions in NCT03457974: saliva.

What condition does NCT03457974 study?

NCT03457974 studies Cardiac Disease, Dental Caries.

Is NCT03457974 still recruiting?

NCT03457974 is currently completed. Last updated 8 March 2018.

Last reviewed 2018-03-08 · How we verify

NCT03457974

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Saliva Profiles in Children With Congenital Heart Disease

Completed NA Last updated 8 March 2018

What this trial tests

NA trial testing saliva in Cardiac Disease in 84 participants. Completed in 1 January 2012.

Timeline

1 January 2011

Primary endpoint
1 January 2012

1 January 2012

Quick facts

Lead sponsor	Istanbul University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	84
Start date	1 January 2011
Primary completion	1 January 2012
Estimated completion	1 January 2012

Drugs / interventions tested

saliva — full drug profile →

Conditions studied

Cardiac Disease — all drugs for Cardiac Disease →
Dental Caries — all drugs for Dental Caries →

Sponsor

Istanbul University

Who can join

Adults 3 to 12, any sex, with Cardiac Disease or Dental Caries. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary buffering capacity and drug intake such as angiotensin-converting enzyme (ACE) inhibitors. If such relationships exist, they might be employed to patient caries -prevention treatment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Saliva profiles in children with congenital heart disease.
Koruyucu M, Batu S, Bayram M, Uslu E, et al · · 2020 · cited 3× · PMID 32518911 · DOI 10.26650/eor.20200087

Verify or expand the search:

Other trials of saliva

Trials testing the same drug.

NCT04804137 — Immune Response Under Immunotherapy in Metastatic NSCLC: Sputum, Blood Samples and Microbioata Study · completed

Other recruiting trials for Cardiac Disease

Currently open trials in the same condition.

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NCT07217392 — Left Bundle Branch Area Pacing (LBBAP) PMCF Study · NA · recruiting
NCT05877755 — Validation of Multi-contrast, High-resolution Cardiac Magnetic Resonance Imaging · NA · recruiting

Other Istanbul University trials

Trials by the same sponsor.

NCT07472946 — Whole-Body Vibration Exercise in Patients With Parkinson's Disease · NA · not yet recruiting
NCT07433894 — Scoliosis and Functional Outcomes in Children With Juvenile Idiopathic Arthritis · not yet recruiting
NCT07420049 — Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study · not yet recruiting
NCT07415967 — The Effect of a Dual-Task Technique-Based Exercise Program on Clinical Outcomes in Rotator Cuff Related Shoulder Pain · NA · recruiting
NCT07473024 — pEEG-Guided Anesthesia and Behavioral Outcomes in Children · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03457974 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istanbul University
Last refreshed: 8 March 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03457974.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing