Last reviewed · How we verify
NCT03457831
Status Epilepticus in the Critically Ill Patients
trial in Status Epilepticus in 1,000 participants. Currently enrolling.
31 December 2028
Quick facts
| Lead sponsor | Ictal Group |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 28 February 2018 |
| Primary completion | 31 December 2028 |
| Estimated completion | 31 December 2028 |
| Sites | 20 locations across France |
Conditions studied
- Status Epilepticus — all drugs for Status Epilepticus →
Sponsor
Ictal Group
Who can join
18 and older, any sex, with Status Epilepticus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Convulsive and Non Convulsive Status Epilepticus (SE) and Pseudo Status Epilepticus prospective registry. Data collection using a standardized form : demographic data and data related to the SE, including circumstances of onset, dates and times of onset and of seizure control, on-scene clinical findings, clinical features of the seizures, pre-hospital and hospital care providers, timing of antiepileptic and supportive treatments, results of etiological investigations, cause of SE, type and dosage of antiepileptic drugs. Dates and times of EEG monitoring, EEG results. Outcomes including vital status and Glasgow Outcome Scale score at ICU and hospital discharge, day-90 and 1-year after SE and determined based on data in the ICU and/or neurologist charts and/or patients phone interview.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Multicentre observational status-epilepticus registry: protocol for ICTAL.
Jacq G, Chelly J, Quenot JP, Soulier P, et al · · 2022 · cited 6× · PMID 35168989 · DOI 10.1136/bmjopen-2021-059675 -
Electrocardiographic Changes at the Early Stage of Status Epilepticus: First Insights From the ICTAL Registry.
Chinardet P, Gilles F, Cochet H, Chelly J, et al · · 2023 · cited 3× · PMID 36533915 · DOI 10.1097/ccm.0000000000005768 -
Management and outcomes of critically ill adult patients with convulsive status epilepticus and preadmission functional impairments.
Vieille T, Jacq G, Merceron S, Huriaux L, et al · · 2023 · cited 1× · PMID 36803873 · DOI 10.1016/j.yebeh.2023.109083 -
Assessment of health-related quality of life, cognitive, physical and psychological impairments in critically ill adults after status epilepticus (POSEIDON 2): protocol for a multicentre longitudinal study.
Legriel S, Bernard C, Sboui G, Sigaud F, et al · · 2026 · PMID 41775483 · DOI 10.1136/bmjopen-2025-112563
Verify or expand the search:
- PubMed search for NCT03457831
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Status Epilepticus
Currently open trials in the same condition.
- NCT06401707 — PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest · Phase 2 · recruiting
- NCT06194747 — Improving Status Epilepticus Treatment Times · NA · recruiting
- NCT06017973 — The Role of Imaging in the Diagnosis, Management and Prognosis of Possible Non-convulsive Status Epilepticus · NA · recruiting
- NCT05851391 — buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest · Phase 2 · recruiting
- NCT05839418 — Sustained Effort Network for Treatment of Status Epilepticus/European Academy of Neurology Registry on Refractory Status · recruiting
Other Ictal Group trials
Trials by the same sponsor.
- NCT04320472 — Acute Encephalopathy in Critically Ill Patients With COVID-19 · unknown
- NCT03545776 — Critical Care EEG Course · completed
- NCT03470467 — Posterior Reversible Encephalopathy Syndrome in the Critically Ill Patients · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03457831 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ictal Group
- Last refreshed: 22 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03457831.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing