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NCT03455530

Work Should Not Hurt You: Reduction of Hazardous Exposures in Small Businesses Through a Community Health Worker Intervention

Completed NA Results posted Last updated 10 July 2025
What this trial tests

NA trial testing Industrial Hygiene-Enhance Community Health Worker Intervention in Community Health Aides in 268 participants. Completed in 22 January 2024.

Timeline
21 February 2020
Primary endpoint
22 January 2024
22 January 2024

Quick facts

Lead sponsorUniversity of Arizona
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposeother
Enrollment268
Start date21 February 2020
Primary completion22 January 2024
Estimated completion22 January 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Arizona

Who can join

18 and older, any sex, with Community Health Aides or Industrial Hygiene. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Change in Volatile Organic Chemical Concentrations From Pre- to Post-Intervention Primary · 6 months

The primary outcome is the change in average total volatile organic chemical exposures for each business from pre- to post- intervention.

GroupValue95% CI
Intervention Group - Beauty Salon27381720 – 4358
Delayed Intervention Group - Beauty Salon38752471 – 6077
Intervention Group - Auto Shops523267 – 1026
Delayed Intervention - Auto Shops225116 – 435

Sponsor's own description

This project aims to reduce negative health outcomes in small businesses that primarily employ high-risk Latino workers by characterizing their exposures to hazardous chemicals and assessing if a community health worker (CHW) intervention is effective at decreasing these exposures. Although preventable by definition, occupational disease and injuries are leading causes of death in the United States, with a disproportionate burden faced by Latinos. Small businesses pose a particular risk. They are more likely to employ low-wage Latino workers, and often use hazardous solvents including volatile organic chemicals that can cause asthma, cancer, cardiovascular, and neurological disease; yet their workers lack access to culturally and linguistically appropriate occupational health and pollution prevention information due to economic, physical, and social barriers. CHW-led interventions and outreach in Latino communities have documented increased access to health care and health education and reduced workplace exposures among farmworkers. CHWs are an innovative method to bridge the gap between these small business communities and other stakeholders. The proposed project will capitalize on established partnerships between the University of Arizona, the Sonora Environmental Research Institute, Inc. and the El Rio Community Health Center. A community-engaged research framework will be used to complete the following specific aims: 1) quantify and identify exposures to hazardous chemicals in the two high risk small business sectors common in our target area (i.e., auto repair shops and beauty salons); 2) work collaboratively with business owners, trade groups, workers and CHWs to design an industrial hygiene - enhanced CHW intervention tailored for each small business sector; and 3) conduct a cluster randomized trial to evaluate the effectiveness of the CHW intervention at reducing workplace exposures to volatile organic compounds and assess which factors led to successful utilization of exposure control strategies in both male and female-dominated businesses. Businesses will be randomized to either an intervention or delayed intervention group, both of which will receive incentives to participate including worksite health screenings. CHWs will work closely with business owners and employees to select and implement exposure-strategies appropriate for their worksite using a menu of complementary strategies of varying complexity and cost. This innovative project has the potential to directly reduce occupational health disparities through a CHW intervention that moves beyond providing occupational health education. The intervention will overcome current barriers by helping marginalized Latino workers and small business owners who may have limited education, literacy, and computer skills to understand the hazards associated with their work, and will empower them to have greater control over their occupational exposures, with the ultimate goal of preventing occupational disease and reducing health disparities.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Community health worker intervention to reduce worker exposure to volatile organic compounds in small business auto and beauty shops in a marginalized community: A cluster randomized controlled trial.
    Gutenkunst SL, Lothrop N, Quijada C, Chaires M, et al · · 2026 · PMID 42044132 · DOI 10.1371/journal.pone.0346356

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03455530.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing