NCT03453398: Turnisti

Effects of Shift Work on Nurse Staff Health

Completed NA Last updated 18 January 2020

What this trial tests

NA trial testing Shifts working hours with different schedules in Shift Work Type Circadian Rhythm Sleep Disorder in 71 participants. Completed in 15 January 2020.

Timeline

23 January 2018

Primary endpoint
30 December 2019

15 January 2020

Quick facts

Lead sponsor	I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	71
Start date	23 January 2018
Primary completion	30 December 2019
Estimated completion	15 January 2020
Sites	1 location across Italy

Drugs / interventions tested

• Shifts working hours with different schedules

Conditions studied

• Shift Work Type Circadian Rhythm Sleep Disorder — all drugs for Shift Work Type Circadian Rhythm Sleep Disorder →
• Chronobiology Disorders — all drugs for Chronobiology Disorders →
• Mood Swing — all drugs for Mood Swing →
• Physical Activity — all drugs for Physical Activity →

Sponsor

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio — full company profile →

Who can join

Adults 18 to 70, any sex, with Shift Work Type Circadian Rhythm Sleep Disorder or Chronobiology Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Shift work deeply impacts on temporal organization leading to a circadian desynchronization, which translates into a worsening of the sleep quality and work ability during waking hours. Furthermore, also the fine motor control skills and the subjective mood profile could undergo modifications in relation to the acquired sleep debt. The misalignment between working time and physiological/behavioral functions could have negative influences on the levels of spontaneous daily activity, with possible alteration of the activity-rest rhythm of the worker, especially in clinics.

In relation to the participants' chronotype, the aim of this project will be to evaluate the effect of irregular working hours (shift work) on (i) the sleep quality, (ii) the circadian rhythm of activity levels and, (iii) the motor control. These assessments will help to identify the shift type with less impact on the health status in a nurse cohort.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Reduced Neuromuscular Performance in Night Shift Orthopedic Nurses: New Insights From a Combined Electromyographic and Force Signals Approach.
   Cè E, Doria C, Roveda E, Montaruli A, et al · · 2020 · cited 11× · PMID 32695018 · DOI 10.3389/fphys.2020.00693
2. Effects of Shift Work in a Sample of Italian Nurses: Analysis of Rest-Activity Circadian Rhythm.
   Galasso L, Mulè A, Castelli L, Cè E, et al · · 2021 · cited 9× · PMID 34444128 · DOI 10.3390/ijerph18168378
3. Differences in Daytime Activity Levels and Daytime Sleep Between Night and Day Duty: An Observational Study in Italian Orthopedic Nurses.
   Roveda E, Castelli L, Galasso L, Mulè A, et al · · 2021 · cited 7× · PMID 33732163 · DOI 10.3389/fphys.2021.628231