Who is sponsoring NCT03452124?

NCT03452124 is sponsored by University of Athens.

What drugs are being tested in NCT03452124?

Interventions in NCT03452124: I quit ordinary smoking (IQOS), Conventional cigarette.

What condition does NCT03452124 study?

NCT03452124 studies Smoking Cessation.

Is NCT03452124 still recruiting?

NCT03452124 is currently status unknown. Last updated 24 April 2020.

Last reviewed 2020-04-24 · How we verify

NCT03452124

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effects of I Quit Ordinary Smoking on the Arterial Wall and Endothelial Glycocalyx Properties of Smokers

Status unknown NA Last updated 24 April 2020

What this trial tests

NA trial testing I quit ordinary smoking (IQOS) in Smoking Cessation in 90 participants. Status unknown.

Timeline

30 March 2018

Primary endpoint
31 December 2020

30 June 2021

Quick facts

Lead sponsor	University of Athens
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	prevention
Enrollment	90
Start date	30 March 2018
Primary completion	31 December 2020
Estimated completion	30 June 2021
Sites	1 location across Greece

Drugs / interventions tested

I quit ordinary smoking (IQOS)
Conventional cigarette

Conditions studied

Smoking Cessation — all drugs for Smoking Cessation →

Sponsor

University of Athens

Who can join

Adults 18 to 60, any sex, with Smoking Cessation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

I quit ordinary smoking (IQOS) is proposed as a bridge to smoking cessation. In this study the investigators will examine its effects on aortic elasticity, glycocalyx integrity, and exhaled carbon monoxide (CO) concentration, both acutely and after 1 month of use.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Differential effects of heat-not-burn and conventional cigarettes on coronary flow, myocardial and vascular function.
Ikonomidis I, Vlastos D, Kostelli G, Kourea K, et al · · 2021 · cited 17× · PMID 34083663 · DOI 10.1038/s41598-021-91245-9
Critical appraisal of interventional clinical trials assessing heated tobacco products: a systematic review.
Braznell S, Van Den Akker A, Metcalfe C, Taylor GMJ, et al · · 2024 · cited 15× · PMID 36347620 · DOI 10.1136/tc-2022-057522
Impact of heated tobacco products on biomarkers of potential harm and adverse events: a systematic review and meta-analysis.
Braznell S, Dance S, Hartmann-Boyce J, Gilmore A. · · 2026 · cited 3× · PMID 40300839 · DOI 10.1136/tc-2024-059000
Differential effects of heat-not-burn, electronic, and conventional cigarettes on endothelial glycocalyx.
Ikonomidis I, Katogiannis K, Kourea K, Kostelli G, et al · · 2023 · cited 3× · PMID 39044785 · DOI 10.1093/ehjimp/qyad008

Verify or expand the search:

Other recruiting trials for Smoking Cessation

Currently open trials in the same condition.

NCT07420621 — Preliminary Effectiveness of Enhanced Text Message + Incentives · NA · recruiting
NCT07224087 — Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients · Phase 1 · recruiting
NCT07331519 — Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer · NA · recruiting
NCT07210567 — Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors · NA · recruiting
NCT07129590 — Trauma-Informed Care for Smoking Cessation for Pregnancy · NA · recruiting

Other University of Athens trials

Trials by the same sponsor.

NCT07469943 — The Effect of Sodium Glucose Co-trnasportert Type 2 Inhibitors on Arterial Stiffness, Endothelial Glycocalyx Thickness a · recruiting
NCT07254819 — Cotinus Coggygria Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients · NA · completed
NCT07069010 — Burnout Syndrome in the Intensive Care Unit Before and During a Palliative Care Trial · recruiting
NCT06766097 — Chios Mastic Toothpaste and Halitosis and Oral Hygiene in Orthodontic Patients · NA · not yet recruiting
NCT06885970 — The Effect of Cytisine Treatment for Smoking Cessation on Cardiovascular Function in Adult Smokers · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03452124 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Athens
Last refreshed: 24 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03452124.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing