Last reviewed · How we verify
NCT03451877
TGFB1 And LAMA1 Gene Polymorphisms in High Myopia
NA trial testing TGFB1 AND LAMA1 GENE POLYMORPHISMS in High Myopia in 151 participants. Completed in 1 June 2017.
1 December 2016
Quick facts
| Lead sponsor | Ege University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | screening |
| Enrollment | 151 |
| Start date | 1 December 2012 |
| Primary completion | 1 December 2016 |
| Estimated completion | 1 June 2017 |
Drugs / interventions tested
- TGFB1 AND LAMA1 GENE POLYMORPHISMS
Conditions studied
- High Myopia — all drugs for High Myopia →
- Gene Mutations — all drugs for Gene Mutations →
Sponsor
Ege University
Who can join
Adults 3 to 13, any sex, with High Myopia or Gene Mutations. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators aimed to investigate TGFB1 and LAMA1 gene polymorphisms in children with high myopia in order to determine the genetic basis of large myopic shifts causing severe visual impairment and complications. Seventy-four children with high myopia (≥6 diopters \[D\]; study group) and 77 emmetropic children (±0.5D; control group) were included. Genetic and polymorphism analyses were performed in the Medical Genetics Laboratory using DNA purified from the patients' blood samples.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03451877
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for High Myopia
Currently open trials in the same condition.
- NCT07052825 — The Role of Capsular Tension Rings in Intraocular Lens Stability in High Myopia Cataract Patients: A Prospective Self-Co · NA · recruiting
- NCT06264830 — 3D Visualization System in Highly Myopic Cataract Operation · NA · recruiting
- NCT06162234 — Wuhan High Myopia Study · recruiting
- NCT05850936 — Effect of IOP Lowering on Progressive HM · NA · active not recruiting
- NCT05550740 — Repeated Low-Level Red-Light Therapy for Shortening Axial Length · NA · active not recruiting
Other Ege University trials
Trials by the same sponsor.
- NCT07468227 — Effect of Helfer Skin Tap and Vibration on Pain and Fear in Children During Intramuscular Injection · NA · not yet recruiting
- NCT07473050 — Virtual Reality-Based 'Health at My Feet' Program for Individuals With Type 2 Diabetes · NA · not yet recruiting
- NCT06955338 — Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children · NA · not yet recruiting
- NCT07344532 — Effect of Preoperative Abdominal Effleurage on Postoperative Constipation · NA · not yet recruiting
- NCT07417748 — Kinesthetic Exercises on Adults · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03451877 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ege University
- Last refreshed: 5 March 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03451877.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing