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NCT03449095

Understanding Alcohol Reward in Social Context

Completed NA Results posted Last updated 31 July 2024
What this trial tests

NA trial testing Alcohol in Alcohol Drinking in 640 participants. Completed in 5 July 2023.

Timeline
4 November 2017
Primary endpoint
5 July 2023
5 July 2023

Quick facts

Lead sponsorUniversity of Illinois at Urbana-Champaign
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designfactorial
Maskingsingle
Primary purposebasic science
Enrollment640
Start date4 November 2017
Primary completion5 July 2023
Estimated completion5 July 2023
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Illinois at Urbana-Champaign

Who can join

Adults 21 to 30, any sex, with Alcohol Drinking or Alcohol Use Disorder. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Self-Reported Emotion Primary · during the laboratory session, up to 9 hours

Positive and negative emotion will be assessed during the laboratory beverage-administration session via self-report on the "8-item Mood Measure." This measure yields two subscales (positive emotion; negative emotion) each ranges from 1 to 6. For positive mood, higher value represents increased alcohol reward. For negative mood, lower value represents increased alcohol reward.

Positive Emotion
GroupValue95% CI
Alcohol Administration3.49± 1.085
Control Beverage Administration2.98± 1.101
Negative Emotion
GroupValue95% CI
Alcohol Administration0.32± 0.447
Control Beverage Administration0.673± 0.750
Self-Reported Social Reinforcement Primary · during the laboratory session, up to 9 hours

Social reinforcement will be assessed using an index of perceived social closeness as well as a modified version of the Perceived Group Reinforcement Scale. The score of the scale ranges from 1 to 9. Higher score indicates increased alcohol reward.

GroupValue95% CI
Alcohol Administration7.471± 1.129
Control Beverage Administration7.180± 1.155

Sponsor's own description

In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Alcohol narrows physical distance between strangers.
    Gurrieri L, Fairbairn CE, Sayette MA, Bosch N. · · 2021 · cited 23× · PMID 33972448 · DOI 10.1073/pnas.2101937118
  2. The effect of acute alcohol intoxication on alcohol cue salience: An event-related brain potential study.
    Kang D, Kang D, Fairbairn CE, Lee Z, et al · · 2022 · cited 6× · PMID 34516169 · DOI 10.1037/adb0000779
  3. Where to Look? Alcohol, Affect, and Gaze Behavior During a Virtual Social Interaction.
    Ariss T, Fairbairn CE, Sayette MA, Velia BA, et al · · 2023 · cited 5× · PMID 37229513 · DOI 10.1177/21677026221096449
  4. The impact of alcohol intoxication on extended vigilance and rest-break recovery.
    Yang R, Patel TN, Fairbairn CE, Benjamin AS. · · 2025 · cited 1× · PMID 39971885 · DOI 10.3758/s13414-025-03029-2
  5. The impact of alcohol on brain response in social context: A hyperscanning alcohol-administration trial.
    Kang D, Fairbairn CE, Han J, Federmeier KD. · · 2025 · PMID 40939911 · DOI 10.1016/j.neuroimage.2025.121450
  6. Social Influence and Problematic Drinking: Insights from the COVID-19 Pandemic.
    Han J, Fairbairn CE, Creswell KG, Venerable WJ. · · 2025 · PMID 40893627 · DOI 10.1177/21677026251340032

Verify or expand the search:

Other trials of Alcohol

Trials testing the same drug.

Other recruiting trials for Alcohol Drinking

Currently open trials in the same condition.

Other University of Illinois at Urbana-Champaign trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03449095.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing