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NCT03448848
Role of Branched-chain Amino Acids Infusion as Adjunct Therapy Post Liver Surgery for Patients in Intensive Care Unit
NA trial testing BCAA preparation Intravenous infusion in Liver Function Post BCAA Infusion in 60 participants. Completed in 10 September 2020.
27 August 2020
Quick facts
| Lead sponsor | National Hepatology & Tropical Medicine Research Institute |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 60 |
| Start date | 15 March 2018 |
| Primary completion | 27 August 2020 |
| Estimated completion | 10 September 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- BCAA preparation Intravenous infusion — full drug profile →
- sterile normal saline — full drug profile →
Conditions studied
- Liver Function Post BCAA Infusion — all drugs for Liver Function Post BCAA Infusion →
Sponsor
National Hepatology & Tropical Medicine Research Institute
Who can join
Adults 18 to 75, any sex, with Liver Function Post BCAA Infusion. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the impact of intravenous BCAAs infusion as adjunct therapy post liver surgery in intensive care unit (ICU).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Prospective randomized, placebo-controlled study: role of branched-chain amino acids infusion as adjunct therapy post-liver surgery for patients in the intensive care unit.
Mahmoud EIE, Awdallah FF. · · 2025 · cited 2× · PMID 40537743 · DOI 10.1186/s12876-025-03696-3
Verify or expand the search:
- PubMed search for NCT03448848
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03448848 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Hepatology & Tropical Medicine Research Institute
- Last refreshed: 21 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03448848.
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