NCT03446404 is a clinical trial of Standing Computed Tomography in Osteoarthritis, Knee, sponsored by Neil A Segal.

Who is sponsoring NCT03446404?

NCT03446404 is sponsored by Neil A Segal.

What drugs are being tested in NCT03446404?

Interventions in NCT03446404: Standing Computed Tomography.

What condition does NCT03446404 study?

NCT03446404 studies Osteoarthritis, Knee.

Is NCT03446404 still recruiting?

NCT03446404 is currently completed. Last updated 26 May 2021.

Last reviewed 2021-05-26 · How we verify

NCT03446404

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Standing Computed Tomography (SCT) Imaging of the Knee Joint

Completed Last updated 26 May 2021

What this trial tests

trial testing Standing Computed Tomography in Osteoarthritis, Knee in 826 participants. Completed in 9 March 2020.

Timeline

1 March 2016

Primary endpoint
9 March 2020

9 March 2020

Quick facts

Lead sponsor	Neil A Segal
Status	Completed
Study type	OBSERVATIONAL
Enrollment	826
Start date	1 March 2016
Primary completion	9 March 2020
Estimated completion	9 March 2020
Sites	1 location across United States

Drugs / interventions tested

Standing Computed Tomography

Conditions studied

Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →

Sponsor

Neil A Segal

Who can join

Adults 45 to 92, any sex, with Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will help us decide the best way to image the knee for diagnostic purposes: Knee computed tomography vs knee x-ray. The computed tomography will provide a weight bearing 3D view.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Clinical value of weight-bearing CT and radiographs for detecting patellofemoral cartilage visualized by MRI in the MOST study.
Segal NA, Murphy MT, Everist BM, Brown KD, et al · · 2021 · cited 10× · PMID 34332048 · DOI 10.1016/j.joca.2021.07.011

Verify or expand the search:

Other recruiting trials for Osteoarthritis, Knee

Currently open trials in the same condition.

NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03446404 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Neil A Segal
Last refreshed: 26 May 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03446404.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing