NCT03446378 is a NA clinical trial of Anodal tDCS in Stroke, sponsored by Universidade Federal de Pernambuco.

Who is sponsoring NCT03446378?

NCT03446378 is sponsored by Universidade Federal de Pernambuco.

What drugs are being tested in NCT03446378?

Interventions in NCT03446378: Anodal tDCS, Physical therapy, Cathodal tDCS, Sham tDCS.

What condition does NCT03446378 study?

NCT03446378 studies Stroke, Transcranial Direct Current Stimulation.

Is NCT03446378 still recruiting?

NCT03446378 is currently completed. Last updated 6 May 2020.

Last reviewed 2020-05-06 · How we verify

NCT03446378

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

tDCS on Motor Rehabiliation of Post Stroke Patients

Completed NA Last updated 6 May 2020

What this trial tests

NA trial testing Anodal tDCS in Stroke in 60 participants. Completed in 1 March 2019.

Timeline

3 March 2018

Primary endpoint
1 September 2018

1 March 2019

Quick facts

Lead sponsor	Universidade Federal de Pernambuco
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	60
Start date	3 March 2018
Primary completion	1 September 2018
Estimated completion	1 March 2019
Sites	1 location across Brazil

Drugs / interventions tested

Anodal tDCS
Physical therapy
Cathodal tDCS
Sham tDCS

Conditions studied

Stroke — all drugs for Stroke →
Transcranial Direct Current Stimulation — all drugs for Transcranial Direct Current Stimulation →

Sponsor

Universidade Federal de Pernambuco — full company profile →

Who can join

Adults 18 to 70, any sex, with Stroke or Transcranial Direct Current Stimulation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this study, it is wondered whether cortical excitability level could predict/direct the use of transcranial direct current stimulation combined with physical therapy on upper limb rehabilitation of post stroke patients. Furthermore, the study aims to correlate the motor recovery with cortical excitability level. For this purpose, after basal evaluation, patients will be classified according motor function evaluated by Fugl Meyer in following categories: (ii) moderate: more than 19 points on Fulg Meyer (ii) severe: less than 19 points on Fulg Meyer.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke.
Elsner B, Kugler J, Pohl M, Mehrholz J. · · 2020 · cited 80× · PMID 33175411 · DOI 10.1002/14651858.cd009645.pub4
Do Higher Transcranial Direct Current Stimulation Doses Lead to Greater Gains in Upper Limb Motor Function in Post-Stroke Patients?
Pires R, Baltar A, Sanchez MP, Antonino GB, et al · · 2023 · cited 11× · PMID 36674035 · DOI 10.3390/ijerph20021279
Baseline Motor Impairment Predicts Transcranial Direct Current Stimulation Combined with Physical Therapy-Induced Improvement in Individuals with Chronic Stroke.
Baltar A, Piscitelli D, Marques D, Shirahige L, et al · · 2020 · cited 7× · PMID 33299400 · DOI 10.1155/2020/8859394

Verify or expand the search:

Other trials of Anodal tDCS

Trials testing the same drug.

NCT07151729 — Use of Anodal tDCS to Enhance Upper Limb Recovery in Stroke · NA · recruiting
NCT06399731 — Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease · NA · recruiting
NCT04944147 — Cognitive Training and Brain Stimulation in Patients With Post-COVID-19 Cognitive Impairment · NA · completed
NCT04390048 — Balance Training With tDCS for CAI · NA · completed
NCT04817124 — Cognitive Training Combined With Transcranial Direct Current Stimulation in Older Adults in a Home-based Context · NA · completed

Other recruiting trials for Stroke

Currently open trials in the same condition.

NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
NCT07356011 — Exoskeleton for Balance · NA · recruiting
NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting

Other Universidade Federal de Pernambuco trials

Trials by the same sponsor.

NCT07366411 — taVNS on Functional Mobility in People With DP · Phase 2 · not yet recruiting
NCT07132021 — Efficacy of Trans-auricular Vagus Nerve Stimulation on Upper Extremity Motor Recovery in Stroke Survivors · Phase 2 · recruiting
NCT07149233 — Effectiveness of Inspiratory Muscle Training on Sleep in Patients With Obstructive Sleep Apnea · NA · enrolling by invitation
NCT06886386 — TsDCS and Physical Therapy After Incomplete Spinal Cord Injury · NA · enrolling by invitation
NCT07523126 — EFFECT OF TRANSCUTANEOUS ELECTRONEURO-STIMULATION OF THE VAGUS NERVE ON JOINT PAIN SEQUELAE OF CHIKUNGUNYA FEVER IN THE · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03446378 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidade Federal de Pernambuco
Last refreshed: 6 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03446378.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing