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Use of the Ozone in Periodontal Treatment
The purpose of this study is to evaluate the clinicaland laboratory (as oxidative stress and pro-inflammatory mediators) effects of the use of gaseous ozone in periodontal treatment in addition to scaling and root planning. The study population consisted of 40 patients with CP (chronic periodontitis). It was performed with two groups; The Test Group, and the Control Group. SRP plus gaseous ozone \[1 W (100 mJ, 10 Hz)\] was applied to the Test Group. The Control Group, on the other hand, had only SRP.The clinical periodontal parameters were performed and saliva samples were taken before SRP (baseline) and 1 month after treatment. The periodontal examination involved assessing the plaque index, gingival index , probing depth, and clinical attachment level. The total antioxidant status, total oxidant status, nitric oxide, 8-hidroxi-deoksiguanosine, myeloperoxidase, glutathione, malondialdehyde and transforming growth factor-beta levels were determined in the saliva samples.
Details
| Lead sponsor | Çanakkale Onsekiz Mart University |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 40 |
| Start date | Tue May 01 2012 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Thu Aug 11 2016 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Chronic Periodontitis
Interventions
- Gaseous ozone
- SRP plus placebo
Countries
Turkey (Türkiye)