NCT03435159

Effects of Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population

Completed NA Last updated 15 February 2018

What this trial tests

NA trial testing Doppler Ultrasonography in Vertebral Artery Dissection, Traumatic in 30 participants. Completed in 28 April 2017.

Timeline

17 February 2017

Primary endpoint
28 April 2017

28 April 2017

Quick facts

Lead sponsor	Bahçeşehir University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	screening
Enrollment	30
Start date	17 February 2017
Primary completion	28 April 2017
Estimated completion	28 April 2017
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Doppler Ultrasonography
• Manual Chiropractic Spinal Manipulation
• Instrumental Chiropractic Spinal Manipulation

Conditions studied

• Vertebral Artery Dissection, Traumatic — all drugs for Vertebral Artery Dissection, Traumatic →
• Neck Pain — all drugs for Neck Pain →

Sponsor

Bahçeşehir University

Who can join

Adults 20 to 40, any sex, with Vertebral Artery Dissection, Traumatic or Neck Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

After lumbar pain, neck pain is the most common cause of patients needing chiropractic care; the second most common cause of spinal manipulation use (1). Manipulation and mobilization are commonly used by chiropractors, osteopaths and manipulative physiotherapists in the treatment of neck pain. Many studies show that the Activator instrument is also used for this purpose in the chiropractic profession (2) There are several published case reports that relate to neck manipulation to vertebral artery dissection and stroke. The prevailing theory is that the neck extension and / or rotation may damage the vertebral artery in the foramen transversarium, especially at the C1-C2 level (2). However, most cases of extracranial vertebral artery dissection are thought to be spontaneous (3).

In the literature, there have been no studies investigating the effects of instrument-assisted spinal manipulation on vertebrobasilar and internal carotis arteries. the aim of this study to compare the effect of manual and instrumental spinal manipulation on blood flow parameters of vertebrobasilar and internal carotis arteries on healthy persons which have mechanical neck pain and asymptomatic in vertebrobasilar insufficiency test.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effects of Manual Versus Instrumental Spinal Manipulation on Blood Flow of the Vertebral and Internal Carotid Arteries in Participants With Chronic Nonspecific Neck Pain: A Single-Blind, Randomized Study.
   Kocabey B, Karagözoğlu Coşkunsu D, Güven K, Ağaoğlu MH, et al · · 2023 · cited 4× · PMID 36844987 · DOI 10.1016/j.jcm.2022.05.006