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NCT03433287
Chronic Recurrent Multifocal Osteomyelitis - a Bacterial Cause?
NA trial testing 18F-NaF-PET/MRI in Chronic Recurrent Multifocal Osteomyelitis in 15 participants. Status unknown.
1 January 2022
Quick facts
| Lead sponsor | Rigshospitalet, Denmark |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 15 |
| Start date | 1 November 2015 |
| Primary completion | 1 January 2022 |
| Estimated completion | 1 December 2022 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- 18F-NaF-PET/MRI
Conditions studied
- Chronic Recurrent Multifocal Osteomyelitis — all drugs for Chronic Recurrent Multifocal Osteomyelitis →
Sponsor
Rigshospitalet, Denmark
Who can join
Adults 0 to 18, any sex, with Chronic Recurrent Multifocal Osteomyelitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Chronic recurrent multifocal osteomyelitis (CRMO) is an immune-mediated chronic inflammatory self- limiting disease with non-suppurative inflammation involving one or multiple bone foci. A bacterial etiology has not yet been proven, but the investigators hypothesize that CRMO is caused by chronic infection. Using existing knowledge of chronic infections combined with sensitive molecular techniques, the hope is to elucidate the cause of CRMO by proving or disproving bacteria as the underlying etiology. In addition, a novel method, 18F-NaF-PET/MRI, will be investigated as to which it can improve diagnosis of CRMO. The investigators hypothesize that 18F-NaF-PET/MRI will have higher diagnostic accuracy than 99m-diphosphonate planar bone scintigraphy and SPECT/CT.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03433287
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other recruiting trials for Chronic Recurrent Multifocal Osteomyelitis
Currently open trials in the same condition.
- NCT07483853 — Reliability and Validation of the WB-MRI Radiological Score in CRMO · recruiting
Other Rigshospitalet, Denmark trials
Trials by the same sponsor.
- NCT07401368 — Clinicians' Trust in AI-Based Fetal Growth Estimates · NA · not yet recruiting
- NCT07442357 — The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation Trial · NA · not yet recruiting
- NCT07528729 — Alcohol as a Modifiable Risk Factor for Atrial Fibrillation · NA · not yet recruiting
- NCT07511439 — Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission · Phase 4 · not yet recruiting
- NCT07467187 — Invasive Home Ventilation in Denmark · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03433287 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rigshospitalet, Denmark
- Last refreshed: 24 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03433287.
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