Last reviewed · How we verify
NCT03430765
Preventing Persistent Pain and Reducing Depressive and Anxious Symptoms Following Mastectomy and Lumpectomy
NA trial testing Acceptance and Commitment Therapy in Persistent Postsurgical Pain in 62 participants. Completed in 22 November 2017.
19 November 2017
Quick facts
| Lead sponsor | Katherine Hadlandsmyth |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 62 |
| Start date | 21 June 2015 |
| Primary completion | 19 November 2017 |
| Estimated completion | 22 November 2017 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Acceptance and Commitment Therapy
Conditions studied
- Persistent Postsurgical Pain — all drugs for Persistent Postsurgical Pain →
- Breast Cancer Female — all drugs for Breast Cancer Female →
- Ductal Carcinoma in Situ — all drugs for Ductal Carcinoma in Situ →
Sponsor
Katherine Hadlandsmyth
Who can join
Adults 18 to 100, female only, with Persistent Postsurgical Pain or Breast Cancer Female. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The proposed study will be a pilot randomized controlled trial comparing treatment as usual (TAU) to treatment as usual plus a brief Acceptance and Commitment Therapy (ACT) intervention (TAU + ACT) with mastectomy and lumpectomy patients identified as at-risk for developing persistent post-operative pain. The ACT intervention is a single individual therapy session scheduled two weeks following surgery. Potential participants will be recruited from the University of Iowa Breast Cancer Clinic. A sample size of n = 30 for each arm will be recruited. An attrition rate of 20% is anticipated so the total N to be recruited for the study is 72 participants. Study measures will consist of self-report questionnaires and medical record data. Data will be collected prior to surgery, one-week after surgery, and 3 months after surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A single-session acceptance and commitment therapy intervention among women undergoing surgery for breast cancer: A randomized pilot trial to reduce persistent postsurgical pain.
Hadlandsmyth K, Dindo LN, Wajid R, Sugg SL, et al · · 2019 · cited 27× · PMID 31430830 · DOI 10.1002/pon.5209
Verify or expand the search:
- PubMed search for NCT03430765
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Acceptance and Commitment Therapy
Trials testing the same drug.
- NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting
- NCT07345806 — A Pilot Study on an ACT-Based Program for Individuals With Special Needs and Their Caregivers · NA · recruiting
- NCT07512388 — Acceptance and Commitment Therapy for Post-Stroke Adjustment Via Telerehabilitation · NA · active not recruiting
- NCT06647589 — Acceptance and Commitment Therapy for Religious OCD · NA · recruiting
- NCT06971861 — Just ACT for Student Well-being · NA · recruiting
Other recruiting trials for Persistent Postsurgical Pain
Currently open trials in the same condition.
- NCT05407610 — Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03430765 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Katherine Hadlandsmyth
- Last refreshed: 11 February 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03430765.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing