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NCT03429426: RACTX

Progression of Bone Erosions in Rheumatoid Arthritis Assessed by HR-pQCT and Conventional X-ray

ENROLLING BY INVITATION Last updated 13 January 2021
What this trial tests

trial in Arthritis, Rheumatoid in 625 participants. Enrolling by invitation.

Timeline
15 February 2018
Primary endpoint
1 February 2022
31 December 2026

Quick facts

Lead sponsorAarhus University Hospital
StatusENROLLING BY INVITATION
Study typeOBSERVATIONAL
Enrollment625
Start date15 February 2018
Primary completion1 February 2022
Estimated completion31 December 2026
Sites1 location across Denmark

Conditions studied

Sponsor

Aarhus University Hospital

Who can join

18 and older, any sex, with Arthritis, Rheumatoid. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Today, regular X-ray examination is not sufficiently sensitive for detecting progression of bone destruction in rheumatoid arthritis, but a new type of high-resolution CT scanner, the High-Resolution peripheral Quantitative Computed Tomography (HR-pQCT) can detect very early and minor joint injuries. The purpose of this study is to use HR-pQCT techniques to look at the damage and disease activity progression in the hand and wrist joints of patients with rheumatoid arthritis.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Diagnostic accuracy of high-resolution peripheral quantitative computed tomography and X-ray for classifying erosive rheumatoid arthritis.
    Klose-Jensen R, Therkildsen J, Blavnsfeldt AG, Langdahl BL, et al · · 2022 · cited 10× · PMID 34015091 · DOI 10.1093/rheumatology/keab446
  2. Mapping the bare area and transcortical pores in finger joints: co-location with bone erosions in rheumatoid arthritis.
    Therkildsen J, Klose-Jensen R, Langdahl B, Brüel A, et al · · 2026 · PMID 41571324 · DOI 10.1136/rmdopen-2025-006371

Verify or expand the search:

Other recruiting trials for Arthritis, Rheumatoid

Currently open trials in the same condition.

Other Aarhus University Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03429426.

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