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NCT03429426: RACTX
Progression of Bone Erosions in Rheumatoid Arthritis Assessed by HR-pQCT and Conventional X-ray
trial in Arthritis, Rheumatoid in 625 participants. Enrolling by invitation.
1 February 2022
Quick facts
| Lead sponsor | Aarhus University Hospital |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 625 |
| Start date | 15 February 2018 |
| Primary completion | 1 February 2022 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Denmark |
Conditions studied
- Arthritis, Rheumatoid — all drugs for Arthritis, Rheumatoid →
Sponsor
Aarhus University Hospital
Who can join
18 and older, any sex, with Arthritis, Rheumatoid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Today, regular X-ray examination is not sufficiently sensitive for detecting progression of bone destruction in rheumatoid arthritis, but a new type of high-resolution CT scanner, the High-Resolution peripheral Quantitative Computed Tomography (HR-pQCT) can detect very early and minor joint injuries. The purpose of this study is to use HR-pQCT techniques to look at the damage and disease activity progression in the hand and wrist joints of patients with rheumatoid arthritis.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Diagnostic accuracy of high-resolution peripheral quantitative computed tomography and X-ray for classifying erosive rheumatoid arthritis.
Klose-Jensen R, Therkildsen J, Blavnsfeldt AG, Langdahl BL, et al · · 2022 · cited 10× · PMID 34015091 · DOI 10.1093/rheumatology/keab446 -
Mapping the bare area and transcortical pores in finger joints: co-location with bone erosions in rheumatoid arthritis.
Therkildsen J, Klose-Jensen R, Langdahl B, Brüel A, et al · · 2026 · PMID 41571324 · DOI 10.1136/rmdopen-2025-006371
Verify or expand the search:
- PubMed search for NCT03429426
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other Aarhus University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03429426 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aarhus University Hospital
- Last refreshed: 13 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03429426.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing