Who is sponsoring NCT03428451?

NCT03428451 is sponsored by Ahmed Mohamed ELbadawy.

What drugs are being tested in NCT03428451?

Interventions in NCT03428451: NaCl 3% HS, NaCl 3% HS, NaCl 0.9% NS.

What condition does NCT03428451 study?

NCT03428451 studies Transurethral Resection of Prostate Syndrome.

Is NCT03428451 still recruiting?

NCT03428451 is currently status unknown. Last updated 23 December 2018.

Last reviewed 2018-12-23 · How we verify

NCT03428451

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prophylaxis Versus Treatment Against TURP Syndrome : Role of Hypertonic Saline

Status unknown NA Last updated 23 December 2018

What this trial tests

NA trial testing NaCl 3% HS in Transurethral Resection of Prostate Syndrome in 60 participants. Status unknown.

Timeline

10 February 2018

Primary endpoint
1 December 2018

1 December 2018

Quick facts

Lead sponsor	Ahmed Mohamed ELbadawy
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	60
Start date	10 February 2018
Primary completion	1 December 2018
Estimated completion	1 December 2018
Sites	1 location across Egypt

Drugs / interventions tested

NaCl 3% HS — full drug profile →
NaCl 3% HS — full drug profile →
NaCl 0.9% NS — full drug profile →

Conditions studied

Transurethral Resection of Prostate Syndrome — all drugs for Transurethral Resection of Prostate Syndrome →

Sponsor

Ahmed Mohamed ELbadawy — full company profile →

Who can join

Adults 50 to 80, male only, with Transurethral Resection of Prostate Syndrome. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Serum sodium level measured in mEq/L
Time frame: 72 hours
Hyponatremia was defined as a serum sodium \< 130 mEq/L

Sponsor's own description

This study is designed to investigate the usage \& effects of prophylactic HS preloading, with two different concentrations, to combat the expected dilutional hyponatremia induced by irrigating fluid absorption and to prevent the occurrence of TURP syndrome with its potential complications

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Prophylaxis versus Treatment against Transurethral Resection of Prostate Syndrome: The Role of Hypertonic Saline.
Seif NE, Shehab HA, Elbadawy AM. · · 2020 · cited 1× · PMID 32843802 · DOI 10.4103/aer.aer_148_19

Verify or expand the search:

Other recruiting trials for Transurethral Resection of Prostate Syndrome

Currently open trials in the same condition.

NCT04084938 — Artery Embolization vs Operation of Benign Prostate Hyperplasia · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03428451 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ahmed Mohamed ELbadawy
Last refreshed: 23 December 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03428451.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing