NCT03427112 is a clinical trial of Xin1 Humerus System in Proximal Humeral Fracture, sponsored by AO Research Institute Davos.

Who is sponsoring NCT03427112?

NCT03427112 is sponsored by AO Research Institute Davos.

What drugs are being tested in NCT03427112?

Interventions in NCT03427112: Xin1 Humerus System.

What condition does NCT03427112 study?

NCT03427112 studies Proximal Humeral Fracture.

Is NCT03427112 still recruiting?

NCT03427112 is currently completed. Last updated 1 April 2021.

Last reviewed 2021-04-01 · How we verify

NCT03427112

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessment of the Surgical Handling and Performance of the X-ray-based Tracking and Navigation System "Xin1 Humerus System" Evaluated From 10 Proximal Humerus Plate Fixations

Completed Last updated 1 April 2021

What this trial tests

trial testing Xin1 Humerus System in Proximal Humeral Fracture in 11 participants. Completed in 6 March 2020.

Timeline

4 April 2017

Primary endpoint
6 March 2020

6 March 2020

Quick facts

Lead sponsor	AO Research Institute Davos
Status	Completed
Study type	OBSERVATIONAL
Enrollment	11
Start date	4 April 2017
Primary completion	6 March 2020
Estimated completion	6 March 2020
Sites	1 location across Belgium

Drugs / interventions tested

Xin1 Humerus System

Conditions studied

Proximal Humeral Fracture — all drugs for Proximal Humeral Fracture →

Sponsor

AO Research Institute Davos

Who can join

18 and older, any sex, with Proximal Humeral Fracture. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Xin1 Humerus system is an X-ray-based tracking and navigation system designed to calculate the plate position and all required proximal screw lengths for proximal humerus plate fixation. The aim is to validate the system performance in a clinical context and test the surgical handling of the Xin1 marker in a hospital environment. 10 adults having sustained a proximal humerus fracture and are indicated for plate fixation osteosynthesis will be provided intraoperatively with the Xin1 marker. The system performance is evaluated retrospectively by post-processing the intraoperative X-ray images after surgery

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Generic Implant Positioning Technology Based on Hole Projections in X-Ray Images.
Windolf M, Richards RG. · · 2021 · cited 5× · PMID 33995756 · DOI 10.1115/1.4049979
In Vitro Testing and Clinical Handling of a Novel Implant Positioning Technology for Proximal Humeral Plating.
Windolf M, Knierzinger D, Nijs S, Sermon A, et al · · 2023 · PMID 36984451 · DOI 10.3390/medicina59030450

Verify or expand the search:

Other recruiting trials for Proximal Humeral Fracture

Currently open trials in the same condition.

NCT06416618 — Surgical Versus Non-surgical Treatment of Displaced Proximal Humerus Fracture in Adults Aged 50 to 65 Years · NA · recruiting
NCT05703958 — Exactech Proximal Humerus Fracture Plate System Post Market Clinical Follow-up · recruiting
NCT06444828 — Comparing Outcomes of Non-surgical Versus Surgical Treatment of Shoulder Fractures With Different Shoulder Replacements · NA · active not recruiting
NCT06133920 — Duration of Immobilization After Reverse Total Arthroplasty for Proximal Humerus Fractures · recruiting
NCT04523415 — Researches About Proximal Humerus Fractures · recruiting

Other AO Research Institute Davos trials

Trials by the same sponsor.

NCT04440631 — Gut Microbiome of Patients Undergoing Antibiotic Therapy for Orthopedic Device-related Infection · completed
NCT04056351 — A Research Study to Understand and Predict the Failure of Shoulder Fracture Fixations Using Computer Simulations · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03427112 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by AO Research Institute Davos
Last refreshed: 1 April 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03427112.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing