NCT03420677 (WESA) is a NA clinical trial of Application of tones in Sleep, sponsored by Swiss Federal Institute of Technology.

Who is sponsoring NCT03420677?

NCT03420677 is sponsored by Swiss Federal Institute of Technology.

What drugs are being tested in NCT03420677?

Interventions in NCT03420677: Application of tones, No application of tones.

Is NCT03420677 still recruiting?

NCT03420677 is currently completed. Last updated 3 March 2021.

Last reviewed 2021-03-03 · How we verify

NCT03420677: WESA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Enhancement of Sleep With Wearables

Completed NA Last updated 3 March 2021

What this trial tests

NA trial testing Application of tones in Sleep in 33 participants. Completed in 30 October 2020.

Timeline

7 May 2018

Primary endpoint
5 March 2019

30 October 2020

Quick facts

Lead sponsor	Swiss Federal Institute of Technology
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	basic science
Enrollment	33
Start date	7 May 2018
Primary completion	5 March 2019
Estimated completion	30 October 2020
Sites	1 location across Switzerland

Drugs / interventions tested

Application of tones
No application of tones

Conditions studied

Sleep — all drugs for Sleep →

Sponsor

Swiss Federal Institute of Technology

Who can join

Adults 18 to 84, any sex, with Sleep. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Sleep, specifically deep sleep, plays a central role in healthy brain function, cardio-vascular processes, mood and quality of life. Auditory stimulation during one night of sleep has previously been shown to improve deep sleep and along with memory formation in both young and older adults. Yet, it remains unclear whether long-term auditory stimulation considerably improves sleep quality over longer time periods and how it affects daytime functioning such as cognition, mood, quality of life and peripheral functions (e.g. cardio-vascular). Due to the importance of deep sleep for brain and body and the presence of many conditions that involve reduced deep sleep (e.g. ageing) assessing the beneficial impact of long-term sleep enhancement and its consequences is of central interest.This study will assess the effect of auditory stimulation over two weeks (interleaved with a two weeks washout period) in a cohort of healthy young and older adults using portable recording and stimulation devices.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Auditory deep sleep stimulation in older adults at home: a randomized crossover trial.
Lustenberger C, Ferster ML, Huwiler S, Brogli L, et al · · 2022 · cited 55× · PMID 35603302 · DOI 10.1038/s43856-022-00096-6
Sleep and cardiac autonomic modulation in older adults: Insights from an at-home study with auditory deep sleep stimulation.
Huwiler S, Ferster ML, Brogli L, Huber R, et al · · 2025 · cited 2× · PMID 39223793 · DOI 10.1111/jsr.14328

Verify or expand the search:

Other recruiting trials for Sleep

Currently open trials in the same condition.

NCT07413185 — Relationship Between the Severity of Sleep Deprivation in the First 48 Hours Postpartum, Breastfeeding Motivation, and B · recruiting
NCT07401212 — GUTLINK4KIDS Intervention · NA · recruiting
NCT07497698 — Saffron Extract Supplementation and Sleep Quality in Middle-Aged Adults · NA · recruiting
NCT07213908 — Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth · NA · recruiting
NCT06670287 — The Use of Multiple Sensors to Track Sleep in Nightshift Workers · NA · recruiting

Other Swiss Federal Institute of Technology trials

Trials by the same sponsor.

NCT07182734 — Feasibility of Unsupervised Therapy After Neurological or Orthopaedical Injury in the Home Setting With a Hand Rehabilit · NA · not yet recruiting
NCT06725784 — Feasibility and Cost of Robot-assisted Upper Limb Rehabilitation with Different Levels of Supervision · NA · recruiting
NCT06851130 — Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women · NA · recruiting
NCT06149975 — Feasibility of a Motor-cognitive Training Program in Patients With Traumatic Brain Injury · NA · completed
NCT06116669 — Effects of Oral Iron Supplementation Before vs at Time of Vaccination on Immune Response in Iron Deficient Kenyan Women · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03420677 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Swiss Federal Institute of Technology
Last refreshed: 3 March 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03420677.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing