Last reviewed · How we verify
NCT03419689
Study Looking at Biomarkers in Ovarian Cancer
NA trial testing Tumour tissue collection in Gynecologic Cancer in 510 participants. Currently enrolling.
8 June 2028
Quick facts
| Lead sponsor | University Health Network, Toronto |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 510 |
| Start date | 8 January 2018 |
| Primary completion | 8 June 2028 |
| Estimated completion | 8 June 2028 |
| Sites | 7 locations across Canada |
Drugs / interventions tested
- Tumour tissue collection
- Blood sample collection — full drug profile →
- Ascites Collection
- Fluid Collection
Conditions studied
- Gynecologic Cancer — all drugs for Gynecologic Cancer →
Sponsor
University Health Network, Toronto
Who can join
18 and older, female only, with Gynecologic Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a sample study that will collect biological samples (blood, tumor tissue, ascites, and/or other fluids) from gynecological cancer patients for biomarker research. In addition, the results of the testing done on the samples will be given to the participant's treating physician who may use the information to guide treatment decisions.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Chasing Immune Checkpoint Inhibitors in Ovarian Cancer: Novel Combinations and Biomarker Discovery.
Colombo I, Karakasis K, Suku S, Oza AM. · · 2023 · cited 35× · PMID 37370830 · DOI 10.3390/cancers15123220 -
Double Trouble: Whole-Genome Doubling Distinguishes Early from Late Ovarian Cancer.
Yang SYC, Pugh TJ, Oza AM. · · 2022 · cited 3× · PMID 35476137 · DOI 10.1158/1078-0432.ccr-22-0336 -
Can <i>TP53</i> variant negative be high-grade serous ovarian carcinoma? A case series.
Kasherman L, Garg S, Tchrakian N, Clarke B, et al · · 2021 · cited 2× · PMID 33718561 · DOI 10.1016/j.gore.2021.100729
Verify or expand the search:
- PubMed search for NCT03419689
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Tumour tissue collection
Trials testing the same drug.
- NCT03517917 — Prospective Tissue Collection Research Protocol · completed
- NCT03420118 — Study of Biomarkers in Gynecological Cancers · NA · recruiting
Other recruiting trials for Gynecologic Cancer
Currently open trials in the same condition.
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Other University Health Network, Toronto trials
Trials by the same sponsor.
- NCT06831032 — Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response · NA · recruiting
- NCT06634056 — Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients U · Phase 2 · not yet recruiting
- NCT06836726 — Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resis · Phase 2 · not yet recruiting
- NCT07515651 — Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas · Phase 2 · not yet recruiting
- NCT07509450 — Fecal Microbiota Transplantation in Patients Undergoing Chimeric Antigen Receptor T-cell Therapy and Allogeneic Stem Cel · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03419689 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Health Network, Toronto
- Last refreshed: 4 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03419689.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing