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NCT03412721
Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children
NA trial testing Laser analgesic procedure in Caries, Dental in 41 participants. Completed in 8 September 2019.
1 May 2019
Quick facts
| Lead sponsor | Plovdiv Medical University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 41 |
| Start date | 6 October 2018 |
| Primary completion | 1 May 2019 |
| Estimated completion | 8 September 2019 |
| Sites | 1 location across Bulgaria |
Drugs / interventions tested
- Laser analgesic procedure
- Placebo analgesic procedure
Conditions studied
- Caries, Dental — all drugs for Caries, Dental →
Sponsor
Plovdiv Medical University
Who can join
Adults 10 to 12, any sex, with Caries, Dental. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to determine the effectiveness of Er:YAG pulse therapy for achieving pulpal analgesia in pediatric patients and to quantify the duration and extent of any effects assessed. Design: a randomized split-mouth study with two-way repeated measures design.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Caries inhibition with CO<sub>2</sub>-laser during orthodontic treatment: a study protocol for a randomized split-mouth controlled clinical trial.
Belcheva AB, Shindova MP. · · 2022 · cited 1× · PMID 35279220 · DOI 10.1186/s13063-022-06117-y -
Efficacy of erbium-doped yttrium aluminium garnet for achieving pre-emptive dental laser analgesia in children: A study protocol for a randomized clinical trial.
Veneva E, Raycheva R, Belcheva A. · · 2018 · cited 1× · PMID 30572467 · DOI 10.1097/md.0000000000013601
Verify or expand the search:
- PubMed search for NCT03412721
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Plovdiv Medical University trials
Trials by the same sponsor.
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- NCT06496906 — Clinical and Radiographic Comparison of Two Minimally Invasive Tooth Extraction Systems · NA · completed
- NCT04903275 — Caries Inhibition With CO2-Laser During Orthodontic Treatment · NA · unknown
- NCT07075354 — Healing Outcomes Following Hydraulic Condensation With a Bioactive Bioceramic Sealer in Root Canal Treatment · NA · completed
- NCT04733196 — Clinical Effectiveness of 5 Different Mouthwashes in the Treatment of Generalised Gingivitis · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03412721 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Plovdiv Medical University
- Last refreshed: 4 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03412721.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing