NCT03412084

A "Stand Up and Move More" Intervention for Older Adults

Completed NA Results posted Last updated 16 December 2020

What this trial tests

NA trial testing Stand up and move more in Sedentary Lifestyle in 84 participants. Completed in 1 December 2019.

Timeline

14 March 2018

Primary endpoint
1 December 2019

1 December 2019

Quick facts

Lead sponsor	University of Wisconsin, Madison
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	84
Start date	14 March 2018
Primary completion	1 December 2019
Estimated completion	1 December 2019
Sites	1 location across United States

Drugs / interventions tested

• Stand up and move more

Conditions studied

• Sedentary Lifestyle — all drugs for Sedentary Lifestyle →

Sponsor

University of Wisconsin, Madison

Who can join

56 and older, any sex, with Sedentary Lifestyle. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Total Sedentary Time Per Day Primary · Baseline, 4 weeks, 12 weeks

Participants wore monitors during the day to assess total sitting time/day

Baseline

Group	Value	95% CI
Stand up Intervention	618	± 119
Control	660	± 153

4 weeks

Group	Value	95% CI
Stand up Intervention	564	± 119
Control	650	± 117

12 weeks

Group	Value	95% CI
Stand up Intervention	602	± 116
Control	617	± 120

Short Physical Performance Battery (SPPB) Score Secondary · Baseline, 4 weeks, 12 weeks

The SPPB is an assessment of physical limitations. It combines scores from a balance test, gait speed test, and a chair stand test. The total possible range of scores is 1-12, higher scores indicate better function/less functional limitations.

Baseline

Group	Value	95% CI
Stand up Intervention	8.05	± 2.46
Control	7.65	± 2.60

4 weeks

Group	Value	95% CI
Stand up Intervention	9.29	± 2.65
Control	7.44	± 2.31

12 weeks

Group	Value	95% CI
Stand up Intervention	10.45	± 2.01
Control	8.00	± 2.81

Sponsor's own description

The purpose of the expanded study is to examine the effectiveness of a "Stand Up and Move More" intervention to reduce sedentary behavior in older adults from underserved communities.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. The Feasibility and Effectiveness of a Community-Based Intervention to Reduce Sedentary Behavior in Older Adults.
   Crombie KM, Leitzelar BN, Almassi NE, Mahoney JE, et al · · 2022 · cited 20× · PMID 33504249 · DOI 10.1177/0733464820987919
2. Translating a "Stand Up and Move More" intervention by state aging units to older adults in underserved communities: Protocol for a randomized controlled trial.
   Crombie KM, Leitzelar BN, Almassi NE, Mahoney JE, et al · · 2019 · cited 6× · PMID 31277151 · DOI 10.1097/md.0000000000016272
3. Intervening to reduce sedentary behavior among African American elders: the "Stand Up and Move More" intervention.
   Leitzelar BN, Almassi NE, Andreae SJ, Winkle-Wagner R, et al · · 2024 · cited 3× · PMID 39291047 · DOI 10.34172/hpp.42548