NCT03407521 is a Phase 4 clinical trial of Misoprostol in Second Trimester Abortion, sponsored by Ain Shams University.

Who is sponsoring NCT03407521?

NCT03407521 is sponsored by Ain Shams University.

What drugs are being tested in NCT03407521?

Interventions in NCT03407521: Misoprostol, isosorbide mononitrate, Placebo.

What condition does NCT03407521 study?

NCT03407521 studies Second Trimester Abortion.

Is NCT03407521 still recruiting?

NCT03407521 is currently completed. Last updated 28 February 2018.

Last reviewed 2018-02-28 · How we verify

NCT03407521

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion

Completed Phase 4 Last updated 28 February 2018

What this trial tests

Phase 4 trial testing Misoprostol in Second Trimester Abortion in 60 participants. Completed in 15 December 2017.

Timeline

12 April 2017

Primary endpoint
22 October 2017

15 December 2017

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	60
Start date	12 April 2017
Primary completion	22 October 2017
Estimated completion	15 December 2017
Sites	1 location across Egypt

Drugs / interventions tested

Misoprostol (Misoprostol) — full drug profile →
isosorbide mononitrate (ISOSORBIDE MONONITRATE) — full drug profile →
Placebo

Conditions studied

Second Trimester Abortion — all drugs for Second Trimester Abortion →

Sponsor

Ain Shams University

Who can join

Adults 16 to 40, female only, with Second Trimester Abortion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

the investigators aimed to study the efficacy and safety of nitric oxide donors when combined with prostaglandins in induction of second trimester abortion expecting that both drugs when used together will be of greater efficiency and associated with less side effects. the study included 60 women with gestational age between 13weeks+0day and 26weeks+6days indicated for pregnancy termination due to maternal or fetal cause.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Misoprostol

Trials testing the same drug.

NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting

Other recruiting trials for Second Trimester Abortion

Currently open trials in the same condition.

NCT06123026 — Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion · Phase 4 · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03407521 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 28 February 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03407521.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing