Prevention of Infections in Cardiac Surgery (PICS) Prevena Study (PICS-Prevena)

NCT03402945 PHASE4 COMPLETED

This vanguard study will be conducted at two study sites in Canada. It is a cluster randomized trial to test a combination of two antibiotics for antibiotic prophylaxis as compared to routine prophylaxis with one single antibiotic, and to test a negative-pressure wound management system (Prevena) versus standard wound dressing to reduce chest wound infections.

Details

Lead sponsor	Population Health Research Institute
Phase	PHASE4
Status	COMPLETED
Enrolment	4107
Start date	Mon Mar 05 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Oct 17 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Surgical Site Infections

Interventions

• Prevena
• Cefazolin
• Vancomycin
• standard wound dressing

Countries

Canada