NCT03401567

Effects of Exercises Combined With Blood Flow Restriction in Healthy Individuals

Completed NA Last updated 21 November 2019

What this trial tests

NA trial testing Exercise group in Healthy Individuals in 60 participants. Completed in 19 November 2019.

Timeline

18 April 2018

Primary endpoint
20 December 2018

19 November 2019

Quick facts

Lead sponsor	Dokuz Eylul University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	60
Start date	18 April 2018
Primary completion	20 December 2018
Estimated completion	19 November 2019
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Exercise group

Conditions studied

• Healthy Individuals — all drugs for Healthy Individuals →

Sponsor

Dokuz Eylul University

Who can join

Adults 18 to 40, any sex, with Healthy Individuals. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Purpose of the study is; to investigate the effect of exercises combined with blood flow restriction on strength, proprioception and functional motor performance in healthy individuals. There is no randomized controlled study of the effect of upper extremity exercises performed by restricting blood flow on the joint sensation of individuals and functional motor performance in healthy individuals. For this reason, purpose of the study is; to investigate the effect of exercises combined with blood flow restriction on strength, proprioception and functional motor performance in healthy individuals. Pain intensity with the numerical pain rating scale (NRS), muscle strength with digital hand dynamometer, shoulder and elbow proprioception with inclinometer, functional motor performance with Upper Extremity Closed Kinetic Chain Stabilization Test, Functional Throwing Performance Index, Single Arm Shot Put Test, Modified Pull-Up Test evaluation of 60 healthy individuals without neck and upper extremity pain, the fracture and surgical history for the upper extremity, cervical and thoracic area that prevent them to participate in the study will be made. Participants will randomly be separated into 2 groups of 30 people each. Elbow bending exercises with blood flow restriction will be performed to the exercise group during 6 weeks for 3 times a week accompanied by a physiotherapist. Control group will continue daily activities and a brochure on strengthening exercises and protection from injuries. Evaluations will be repeated 2 times and analyzed before the treatment and at the end of the 6th week. With the project, the investigators aim to improve the strength, improve proprioception and functional motor performance in healthy individuals by performing exercises restricting blood flow. With the achievement of the targets, exercises combined with blood flow restriction can be considered among the treatments protective for injuries, healing proprioception. The investigators also believe that the project will blaze the trail for the studies to be performed on athletes.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Elbow flexion training with blood flow restriction improves strength, proprioception, and performance in healthy individuals: a randomized controlled trial.
   Yeşilyaprak SS, Dere D. · · 2025 · PMID 41102692 · DOI 10.1186/s12891-025-08768-9