NCT03401177 is a NA clinical trial of Naproxen 500 Mg in Tendon Injuries, sponsored by Bispebjerg Hospital.

Who is sponsoring NCT03401177?

NCT03401177 is sponsored by Bispebjerg Hospital.

What drugs are being tested in NCT03401177?

Interventions in NCT03401177: Naproxen 500 Mg, Placebo Oral Tablet, Heavy resistance training.

What condition does NCT03401177 study?

NCT03401177 studies Tendon Injuries, Achilles Tendinopathy, Inflammation.

Is NCT03401177 still recruiting?

NCT03401177 is currently completed. Last updated 9 July 2020.

Last reviewed 2020-07-09 · How we verify

NCT03401177

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Treatment of Early Phase Achilles Tendinopathy - the Effect of NSAIDs

Completed NA Last updated 9 July 2020

What this trial tests

NA trial testing Naproxen 500 Mg in Tendon Injuries in 70 participants. Completed in 27 April 2020.

Timeline

15 January 2018

Primary endpoint
31 July 2019

27 April 2020

Quick facts

Lead sponsor	Bispebjerg Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	basic science
Enrollment	70
Start date	15 January 2018
Primary completion	31 July 2019
Estimated completion	27 April 2020
Sites	1 location across Denmark

Drugs / interventions tested

Naproxen 500 Mg — full drug profile →
Placebo Oral Tablet — full drug profile →
Heavy resistance training

Conditions studied

Tendon Injuries — all drugs for Tendon Injuries →
Achilles Tendinopathy — all drugs for Achilles Tendinopathy →
Inflammation — all drugs for Inflammation →

Sponsor

Bispebjerg Hospital

Who can join

18 and older, any sex, with Tendon Injuries or Achilles Tendinopathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

this study evaluates the addition of initial short term NSAID treatment to physiotherapy prescribed exercise treatment in patient with early phase tendinopathy. Half of the participants will initially receive NSAID (naproxen) for 7 days, while the other half will receive a placebo, where after both groups will be subjected to 3 months heavy slow resistance training.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Assessment of content validity and psychometric properties of VISA-A for Achilles tendinopathy.
Comins J, Siersma V, Couppe C, Svensson RB, et al · · 2021 · cited 24× · PMID 33705412 · DOI 10.1371/journal.pone.0247152
No Additive Clinical or Physiological Effects of Short-term Anti-inflammatory Treatment to Physical Rehabilitation in the Early Phase of Human Achilles Tendinopathy: A Randomized Controlled Trial.
Malmgaard-Clausen NM, Jørgensen OH, Høffner R, Andersen PEB, et al · · 2021 · cited 18× · PMID 33719579 · DOI 10.1177/0363546521991903

Verify or expand the search:

Other trials of Naproxen 500 Mg

Trials testing the same drug.

NCT06484192 — Pain Control After Lumbar Spine Fusion · Phase 4 · enrolling by invitation
NCT04875702 — Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout · Phase 4 · recruiting
NCT06274151 — Optimal Treatment of Acute Skeletal Muscle Injury · NA · not yet recruiting
NCT05161221 — Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction · Phase 3 · unknown
NCT05154682 — Pain Management After Surgery · Phase 3 · unknown

Other recruiting trials for Tendon Injuries

Currently open trials in the same condition.

NCT07126899 — Hand Tendon Injuries: An Investigation Of Attention Deficit Disorder · active not recruiting
NCT06593912 — Functional and Patient-reported Outcome After Peroneal Tendon Surgery and Different Immobilization Protocols · NA · recruiting

Other Bispebjerg Hospital trials

Trials by the same sponsor.

NCT06872060 — The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance. · NA · not yet recruiting
NCT07373587 — Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy · NA · not yet recruiting
NCT07123558 — Anal Cancer Prevention in High-Risk Categories of Men Who Have Sex With Men · NA · not yet recruiting
NCT07124338 — Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy, a Feasibili · NA · active not recruiting
NCT07096648 — Alert Burden When Monitoring Patients at Home · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03401177 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bispebjerg Hospital
Last refreshed: 9 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03401177.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing