NCT03393728 is a Phase 4 clinical trial of Propanolol in Hyperthyroidism, sponsored by Yaounde Central Hospital.

Who is sponsoring NCT03393728?

NCT03393728 is sponsored by Yaounde Central Hospital.

What drugs are being tested in NCT03393728?

Interventions in NCT03393728: Propanolol.

What condition does NCT03393728 study?

NCT03393728 studies Hyperthyroidism.

Is NCT03393728 still recruiting?

NCT03393728 is currently completed. Last updated 8 January 2018.

Last reviewed 2018-01-08 · How we verify

NCT03393728

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Heart Rate Variability and Hyperthyroidism: Evaluation of the Short-term Effects of Propanolol

Completed Phase 4 Last updated 8 January 2018

What this trial tests

Phase 4 trial testing Propanolol in Hyperthyroidism in 10 participants. Completed in 30 September 2009.

Timeline

1 September 2008

Primary endpoint
30 December 2008

30 September 2009

Quick facts

Lead sponsor	Yaounde Central Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	10
Start date	1 September 2008
Primary completion	30 December 2008
Estimated completion	30 September 2009

Drugs / interventions tested

Propanolol — full drug profile →

Conditions studied

Hyperthyroidism — all drugs for Hyperthyroidism →

Sponsor

Yaounde Central Hospital

Who can join

Adults 18 to 70, any sex, with Hyperthyroidism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Objective: The aim of our study was to evaluate the short term effects of Propanolol on heart rate variability in patients with hyperthyroidism. Design: In ten patients newly diagnosed as having hyperthyroidism and naïve of all treatment specific for hyperthyroidism, we evaluated the short term effects of Propanolol on heart rate variability (HRV). Methods: We measured heart rate variability by power spectral analysis during 2 hours of rest and during Ewing's tests before and after the administration of Propanolol 40mg/12 hours orally for 72 hours.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of propranolol on heart rate variability in hyperthyroidism.
Tankeu AT, Azabji-Kenfack M, Nganou CN, Ngassam E, et al · · 2018 · cited 8× · PMID 29471876 · DOI 10.1186/s13104-018-3224-x

Verify or expand the search:

Other trials of Propanolol

Trials testing the same drug.

NCT04494763 — Primary Prophylaxis for Variceal Bleed in Biliary Atresia · NA · unknown

Other recruiting trials for Hyperthyroidism

Currently open trials in the same condition.

NCT07369063 — Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease · Phase 2 · recruiting
NCT07048548 — Assessment of THL and Potential Risk of Hypothyroidism in Healthcare Workers Exposed to Low-dose Ionizing Radiation · active not recruiting
NCT07472062 — Development of a Non-Invasive Prognostic Test for Graves Orbitopathy · NA · active not recruiting
NCT06794203 — Hyperthyroidism as a Potential Predictive of Worse Outcome of Renal Graft · recruiting
NCT00001159 — Natural History of Thyroid Function Disorders · recruiting

Other Yaounde Central Hospital trials

Trials by the same sponsor.

NCT04790214 — Effect of a Cardiac Rehabilitation Program on Chronic Heart Failure Patients in Yaoundé, Cameroon · NA · unknown
NCT04715295 — Safety and Efficacy of Doxycycline and Rivaroxaban in COVID-19 · Phase 4 · unknown
NCT05013346 — Characteristics of Young-onset Diabetes in Sub-Saharan Africa (YODA) Study · unknown
NCT04255992 — Short Term Cardiovascular Effects and Oxidative Status of Calcium and Vitamin D Supplementation of Postmenopausal Hypert · Phase 4 · completed
NCT04254042 — Comparative Effects of Perindopril and Zofenopril on Blood Pressure Control and Oxidative Status Blacks Hypertensive Pat · Phase 4 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03393728 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yaounde Central Hospital
Last refreshed: 8 January 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03393728.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing