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NCT03391401
Investigation of Microbiome-based Prognostical Biomarkers in Patients With Morbid Obesity and Bariatric Surgery
trial testing Bariatric surgery in Obesity, Morbid in 204 participants. Completed in 31 July 2021.
31 January 2021
Quick facts
| Lead sponsor | St. Franziskus Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 204 |
| Start date | 1 March 2018 |
| Primary completion | 31 January 2021 |
| Estimated completion | 31 July 2021 |
| Sites | 2 locations across Germany |
Drugs / interventions tested
- Bariatric surgery
Conditions studied
- Obesity, Morbid — all drugs for Obesity, Morbid →
- Bariatric Surgery Candidate — all drugs for Bariatric Surgery Candidate →
- NAFLD — all drugs for NAFLD →
- Microbiome — all drugs for Microbiome →
Sponsor
St. Franziskus Hospital
Who can join
18 and older, any sex, with Obesity, Morbid or Bariatric Surgery Candidate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Morbid obesity leads to non-alcoholic fatty liver disease (NAFLD), and not all NAFLD cases benefit from weight loss e.g. after bariatric surgery. Our aim is to find out, which intrahepatic factors and / or biomarkers might be beneficial or can be identified as prognostic factors for remission of NAFLD after weight loss. As other factors such as the microbiome or muscle and fatty tissue also influence the development of obesity and liver diseases, it is planned to examine these parameters before and after bariatric surgery as well. Tissue biopsies will therefore be taken during the surgery, and blood as well as stool samples will be collected and compared for suitable biomarkers before and after the intervention.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03391401
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Obesity, Morbid
Currently open trials in the same condition.
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- NCT06530212 — Sleeve Gastrectomy With Jejuno-ileal Bypass Versus Single Anastomosis Sleeve Jejunal Bypass · NA · recruiting
- NCT06477120 — Time-restricted Eating Among Pregnant Females With Severe Obesity · NA · recruiting
- NCT06119516 — Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study. · NA · recruiting
Other St. Franziskus Hospital trials
Trials by the same sponsor.
- NCT07137676 — Monitoring and Cognitive Appraisal: The Etiology of Psychological Disorders and The Divergence Between Behavioural and S · NA · completed
- NCT04613635 — Stratafix vs. Vicryl OAGB / MGB Suture Study · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03391401 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Franziskus Hospital
- Last refreshed: 7 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03391401.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing