NCT03389906 is a NA clinical trial of Gold in Inflammation, sponsored by Sten Rasmussen, MD, PhD.

Who is sponsoring NCT03389906?

NCT03389906 is sponsored by Sten Rasmussen, MD, PhD.

What drugs are being tested in NCT03389906?

Interventions in NCT03389906: Gold.

What condition does NCT03389906 study?

NCT03389906 studies Inflammation, Osteo Arthritis Knee.

Is NCT03389906 still recruiting?

NCT03389906 is currently completed. Last updated 12 August 2021.

Last reviewed 2021-08-12 · How we verify

NCT03389906

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Inflammation Impact on Pain in Knee Osteoarthritis

Completed NA Last updated 12 August 2021

What this trial tests

NA trial testing Gold in Inflammation in 32 participants. Completed in 1 December 2020.

Timeline

1 December 2017

Primary endpoint
1 December 2018

1 December 2020

Quick facts

Lead sponsor	Sten Rasmussen, MD, PhD
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	32
Start date	1 December 2017
Primary completion	1 December 2018
Estimated completion	1 December 2020
Sites	1 location across Denmark

Drugs / interventions tested

Gold (GOLD) — full drug profile →

Conditions studied

Inflammation — all drugs for Inflammation →
Osteo Arthritis Knee — all drugs for Osteo Arthritis Knee →

Sponsor

Sten Rasmussen, MD, PhD

Who can join

Adults 40 to 75, any sex, with Inflammation or Osteo Arthritis Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to use gold particles as a model compound to modulate specifically and selectively the function of macrophages and mast cells and investigate how this modulates pain and pain sensitization in the osteoarthritic knee assessed by mechanistic pain assessment technologies

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Macrophage: A Potential Target on Cartilage Regeneration.
Fernandes TL, Gomoll AH, Lattermann C, Hernandez AJ, et al · · 2020 · cited 243× · PMID 32117263 · DOI 10.3389/fimmu.2020.00111
Gold micro-particles for knee osteoarthritis.
Rasmussen S, Kjaer Petersen K, Kristiansen MK, Skallerup J, et al · · 2022 · cited 10× · PMID 35076138 · DOI 10.1002/ejp.1909
Intra-articular injection of gold micro-particles with hyaluronic acid for painful knee osteoarthritis.
Rasmussen S, Petersen KK, Aboo C, Andersen JS, et al · · 2024 · cited 2× · PMID 38475764 · DOI 10.1186/s12891-024-07321-4
Intraarticular gold for knee osteoarthritis: An ancillary analysis of biomarkers and outcome of a pilot study.
Rasmussen S, Aboo C, Skallerup J, Stensballe A. · · 2024 · PMID 39291082 · DOI 10.1016/j.ocarto.2024.100514
Intra-articular injection of gold micro-particles for painful knee osteoarthritis
Rasmussen S, Petersen KK, Aboo C, Andersen JS, et al · · 2022 · DOI 10.21203/rs.3.rs-2266972/v1

Verify or expand the search:

Other trials of Gold

Trials testing the same drug.

NCT06186115 — Intraarticular Gold Microparticles for Hip Osteoarthritis · unknown

Other recruiting trials for Inflammation

Currently open trials in the same condition.

NCT07341087 — Skin Inflammation in Perimenopause: A Probiotic Intervention Proof of Concept Trial · NA · recruiting
NCT07479940 — Obesity and Aging: Impacts of Nutritional Counseling and Physical Exercise on Telomeres and Senescence Parameters · NA · active not recruiting
NCT07269847 — Comparing a Healthy Beef-Centric Diet to a Healthy U.S.-Style Diet on Metabolic Health Outcomes in Pre-Diabetic Adults · NA · recruiting
NCT07171450 — Cognitive Remediation · NA · recruiting
NCT07411612 — The Association Between Postoperative Inflammatory and Neurological Serum Biomarker Concentrations and Occurrence of Pos · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03389906 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sten Rasmussen, MD, PhD
Last refreshed: 12 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03389906.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing