Who is sponsoring NCT03388502?

NCT03388502 is sponsored by Rush University Medical Center.

What drugs are being tested in NCT03388502?

Interventions in NCT03388502: Automated Text Messaging (SMS) Bot (intervention group), Routine perioperative education & teaching (control group).

What condition does NCT03388502 study?

NCT03388502 studies Osteoarthritis, Knee, Osteoarthritis, Hip.

Is NCT03388502 still recruiting?

NCT03388502 is currently completed. Last updated 22 November 2023.

Are results published for NCT03388502?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2023-11-22 · How we verify

NCT03388502

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Novel Text-Messaging Bot in Patients Undergoing Joint Arthroplasty

Completed NA Results posted Last updated 22 November 2023

What this trial tests

NA trial testing Automated Text Messaging (SMS) Bot (intervention group) in Osteoarthritis, Knee in 159 participants. Completed in 1 October 2017.

Timeline

21 November 2016

Primary endpoint
1 August 2017

1 October 2017

Quick facts

Lead sponsor	Rush University Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	159
Start date	21 November 2016
Primary completion	1 August 2017
Estimated completion	1 October 2017

Drugs / interventions tested

Automated Text Messaging (SMS) Bot (intervention group)
Routine perioperative education & teaching (control group)

Conditions studied

Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
Osteoarthritis, Hip — all drugs for Osteoarthritis, Hip →

Sponsor

Rush University Medical Center

Who can join

18 and older, any sex, with Osteoarthritis, Knee or Osteoarthritis, Hip. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Time Participating in Home-Based Exercises Primary · over a six-week time period after arthroplasty surgery

Stretching, strengthening, and other rehab-specific exercises counted toward their home-based exercises, while walking was excluded.

Group	Value	95% CI
Text Messaging (SMS) Bot	46.4	± 17.4
Routine Perioperative Instructions	37.7	± 16.3

Knee Range of Motion Secondary · over a six-week time period after arthroplasty surgery

Degrees of flexion and extension of the operative knee will be measured at 6 weeks after surgery.

Group	Value	95% CI
Text Messaging (SMS) Bot	111.9	± 13.3
Routine Perioperative Instructions	108.0	± 12.8

Use of Narcotics/Opiates Secondary · over a six-week time period after arthroplasty surgery

Medications designated as "narcotics" included any medications that contained: hydrocodone, oxycodone, codeine, morphine, or tramadol. Patients were instructed to record their responses during the same two-hour window each day in a daily diary.

Group	Value	95% CI
Text Messaging (SMS) Bot	22.5	± 13.4
Routine Perioperative Instructions	32.4	± 11.8

Visual Analog Scale (VAS) Mood Score Secondary · 6 weeks post-operative

VAS mood scores were collected from patients on the standard ten-point validated scale. If a patient circled two adjacent numbers on their daily diary, an average of the two numbers were assigned for that day. Minimum score 0. Maximum score 10. Higher score is worse outcome (more pain).

Group	Value	95% CI
Text Messaging (SMS) Bot	7.5	± 1.8
Routine Perioperative Instructions	6.5	± 1.7

Calls to the Office Secondary · over a six-week time period after arthroplasty surgery

The number of patient calls to their physicians office were tracked and recorded.

Group	Value	95% CI
Text Messaging (SMS) Bot	0.6	± 0.8
Routine Perioperative Instructions	2.6	± 3.4

Number of Participants Reporting Satisfaction With Instruction Clarity Secondary · over a six-week time period after arthroplasty surgery

Patients were asked to fill out a satisfaction survey six weeks after surgery

Group	Value	95% CI
Text Messaging (SMS) Bot	69
Routine Perioperative Instructions	38

Visits to the Emergency Department (ED) Secondary · over a six-week time period after arthroplasty surgery

The number of visits to the ED were tracked and recorded.

Group	Value	95% CI
Text Messaging (SMS) Bot	0
Routine Perioperative Instructions	4

Adverse events — posted to ClinicalTrials.gov

Time frame: 6 weeks.. Reporting threshold: 0%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Text Messaging (SMS) Bot

Serious: 0/76 (0%)

Deaths: 0/76

Routine Perioperative Instructions

Serious: 4/83 (5%)

Deaths: 0/83

Serious adverse events (1 terms)

Reaction	System	Text Messaging (SMS) Bot	Routine Perioperative Inst…
Presentation to the Emergency Department	Musculoskeletal and connective tissue disorders	—	—

Most-reported serious reactions: Presentation to the Emergency Department.

Data from ClinicalTrials.gov NCT03388502 adverse events section.

Sponsor's own description

This study evaluates the addition of an automated physician-specific text-messaging (SMS) bot in patients undergoing total joint arthroplasty. Half of the patients received the traditional perioperative education and instructions (control group), while the other half were enrolled in their physician's SMS bot (intervention group).

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Osteoarthritis, Knee

Currently open trials in the same condition.

NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting

Other Rush University Medical Center trials

Trials by the same sponsor.

NCT07278076 — Clinical Decision-Making During FEES: The Impact of Residue Amount and Location · NA · not yet recruiting
NCT07088120 — PRECISION-CPR: PRecision-Controlled Ventilation in CPR · NA · not yet recruiting
NCT06894719 — Oral Tranexamic Acid After Total Knee Arthroplasty · Phase 4 · not yet recruiting
NCT06229392 — A Study to Evaluate the Intratumoral Influenza Vaccine Administration in Patients With Breast Cancer · Phase 1 · withdrawn
NCT07452406 — Protocolized Weaning of High-Flow Nasal Cannula in Adult Patients · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03388502 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Rush University Medical Center
Last refreshed: 22 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03388502.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing