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NCT03388385
Acute Effects of Intravenous Iron on Oxidative Stress and Endothelial Dysfunction in Non-dialysis CKD
Phase 4 trial testing Sodium Chloride 0.9% Intravenous Solution in Renal Anemia in 40 participants. Status unknown.
30 December 2020
Quick facts
| Lead sponsor | Carol Davila University of Medicine and Pharmacy |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 20 September 2017 |
| Primary completion | 30 December 2020 |
| Estimated completion | 20 December 2022 |
| Sites | 1 location across Romania |
Drugs / interventions tested
- Sodium Chloride 0.9% Intravenous Solution — full drug profile →
- Ferinject — full drug profile →
Conditions studied
- Renal Anemia — all drugs for Renal Anemia →
- Iron Toxicity — all drugs for Iron Toxicity →
- Oxidative Stress — all drugs for Oxidative Stress →
- Endothelial Dysfunction — all drugs for Endothelial Dysfunction →
Sponsor
Carol Davila University of Medicine and Pharmacy
Who can join
18 and older, any sex, with Renal Anemia or Iron Toxicity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to investigate the effects of acute intravenous iron administration on the endothelial function in non-dialysis Chronic Kidney Disease stages G3-G5 patients with anemia and iron deficiency, in relation to changes in oxidative and nitrosative status.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03388385
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03388385 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Carol Davila University of Medicine and Pharmacy
- Last refreshed: 16 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03388385.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing