Adults 18 to 29, male only, with Risk Behavior or Drug Use. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Illicit Drug UsePrimary· Baseline, 3-month follow-up; 6-month follow-up
The self-reported number of illicit drug use instances (not including marijuana) in the past 30 days
Use at Baseline
Group
Value
95% CI
Couples Health Project (CHP)
3.36
± 8.46
Education
0.84
± 2.34
Use at 3-month follow-up
Group
Value
95% CI
Couples Health Project (CHP)
3.13
± 8.41
Education
0.73
± 1.37
Use at 6-month follow-up
Group
Value
95% CI
Couples Health Project (CHP)
1.17
± 3.79
Education
0.58
± 1.24
Number of HIV Transmission Risk EventsPrimary· 6 months
The self-reported number of events of condomless anal sex (CAS) with casual partners in the past 30 days
Events at Baseline
Group
Value
95% CI
Couples Health Project (CHP)
1.68
± 2.78
Education
1.68
± 2.34
Events at 3-month follow-up
Group
Value
95% CI
Couples Health Project (CHP)
2.13
± 3.61
Education
1.49
± 3.70
Events at 6-month follow-up
Group
Value
95% CI
Couples Health Project (CHP)
0.88
± 1.66
Education
1.05
± 1.82
Marijuana UseSecondary· 6 months
The self-reported number of marijuana drug use instances in the past 30 days
Use at Baseline
Group
Value
95% CI
Couples Health Project (CHP)
9.61
± 11.93
Education
7.02
± 10.24
Use at 3-month follow-up
Group
Value
95% CI
Couples Health Project (CHP)
9.62
± 11.83
Education
5.95
± 10.24
Use at 6-month follow-up
Group
Value
95% CI
Couples Health Project (CHP)
10.00
± 12.43
Education
7.89
± 11.75
Sponsor's own description
This project tests the feasibility, acceptability, and preliminary efficacy of the Couples Health Project (CHP). CHP is a brief (3-session) couples-based Motivational Interviewing intervention which addresses drug use and sexual HIV transmission risk among partnered HIV negative YMSM (ages 18-29). The proposed project includes a randomized controlled trial (RCT) involving 50 couples who are randomized to complete either the CHP intervention or an attention-matched education control condition.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
NCT05522647 — Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients.
· recruiting
NCT07255300 — Follow up Study of Varapodio Trial: Effect of Longevity and Fasting Mimicking Diet on Risk Factors Age Correlated and Bi
· NA
· recruiting
NCT06311838 — Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessne
· NA
· recruiting
NCT06105853 — Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
· NA
· recruiting
NCT03337009 — The Impact of a Web-Based Naloxone Intervention Under Standing Orders to Patients Prescribed Chronic Opioid Therapy
· NA
· active not recruiting
Other Hunter College of City University of New York trials
Trials by the same sponsor.
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· NA
· recruiting
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· recruiting
NCT06126107 — Gain and Loss Framed Text Messaging to Reduce Drinking Among Older Adults
· NA
· completed
NCT06094855 — Effect of Cooling on Balance Performance in Multiple Sclerosis
· recruiting
NCT05544578 — Korean Translation and Validation of the K-HEPI in NYC
· NA
· completed
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hunter College of City University of New York
Last refreshed: 19 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03386110.