NCT03385915 (FinnValve) is a clinical trial of Aortic valve replacement in Aortic Valve Stenosis, sponsored by Turku University Hospital.

Who is sponsoring NCT03385915?

NCT03385915 is sponsored by Turku University Hospital.

What drugs are being tested in NCT03385915?

Interventions in NCT03385915: Aortic valve replacement.

What condition does NCT03385915 study?

NCT03385915 studies Aortic Valve Stenosis.

Is NCT03385915 still recruiting?

NCT03385915 is currently completed. Last updated 10 March 2020.

Last reviewed 2020-03-10 · How we verify

NCT03385915: FinnValve

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Finnish Registry of Transcatheter and Surgical Aortic Valve Replacement for Aortic Valve Stenosis: FinnValve Registry

Completed Last updated 10 March 2020

What this trial tests

trial testing Aortic valve replacement in Aortic Valve Stenosis in 6,463 participants. Completed in 9 March 2020.

Timeline

1 December 2017

Primary endpoint
9 March 2020

9 March 2020

Quick facts

Lead sponsor	Turku University Hospital
Status	Completed
Study type	OBSERVATIONAL
Enrollment	6,463
Start date	1 December 2017
Primary completion	9 March 2020
Estimated completion	9 March 2020
Sites	1 location across Finland

Drugs / interventions tested

Aortic valve replacement

Conditions studied

Aortic Valve Stenosis — all drugs for Aortic Valve Stenosis →

Sponsor

Turku University Hospital

Who can join

18 and older, any sex, with Aortic Valve Stenosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The FinnValve investigators planned a nationwide registry to investigate the early and late outcome of transcatheter aortic valve implantation (TAVI) compared to surgical aortic valve replacement (SAVR) in patients with aortic valve stenosis performed from 2008 to 2017 at five Finnish University Hospitals. Data will be collected in a dedicated electronic case report form.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

Impact of paravalvular regurgitation on the mid-term outcome after transcatheter and surgical aortic valve replacement.
Laakso T, Laine M, Moriyama N, Dahlbacka S, et al · · 2020 · cited 56× · PMID 33057657 · DOI 10.1093/ejcts/ezaa254
Prosthetic valve endocarditis after transcatheter or surgical aortic valve replacement with a bioprosthesis: results from the FinnValve Registry.
Moriyama N, Laakso T, Biancari F, Raivio P, et al · · 2019 · cited 54× · PMID 31113766 · DOI 10.4244/eij-d-19-00247
Comparison of Outcomes After Transcatheter Aortic Valve Replacement vs Surgical Aortic Valve Replacement Among Patients With Aortic Stenosis at Low Operative Risk.
Virtanen MPO, Eskola M, Jalava MP, Husso A, et al · · 2019 · cited 38× · PMID 31199448 · DOI 10.1001/jamanetworkopen.2019.5742
Transcatheter and surgical aortic valve replacement in patients with bicuspid aortic valve.
Husso A, Airaksinen J, Juvonen T, Laine M, et al · · 2021 · cited 27× · PMID 33099681 · DOI 10.1007/s00392-020-01761-3
Favorable outcome of cancer patients undergoing transcatheter aortic valve replacement.
Biancari F, Dahlbacka S, Juvonen T, Virtanen MPO, et al · · 2020 · cited 19× · PMID 32216975 · DOI 10.1016/j.ijcard.2020.03.038
Impact of Major Vascular Complication Access Site Status on Mortality After Transfemoral Transcatheter Aortic Valve Replacement　- Results From the FinnValve Registry.
Laakso T, Moriyama N, Raivio P, Dahlbacka S, et al · · 2020 · cited 11× · PMID 33693226 · DOI 10.1253/circrep.cr-20-0007
Ten-year experience with transcatheter and surgical aortic valve replacement in Finland.
Mäkikallio T, Jalava MP, Husso A, Virtanen M, et al · · 2019 · cited 11× · PMID 31112060 · DOI 10.1080/07853890.2019.1614657
Subtype of atrial fibrillation and the outcome of transcatheter aortic valve replacement: The FinnValve Study.
Jaakkola J, Jaakkola S, Airaksinen KEJ, Husso A, et al · · 2020 · cited 5× · PMID 32915895 · DOI 10.1371/journal.pone.0238953

Verify or expand the search:

Other trials of Aortic valve replacement

Trials testing the same drug.

NCT06964035 — Influence of Original Native Aortic Valve Lesion (Stenosis or Steno-insufficiency vs. Insufficiency) on Post-implant Str · enrolling by invitation
NCT05774808 — Fate of Moderate Secondary Mitral Regurgitation in Patients Undergoing Aortic Valve Surgery for Severe Aortic Regurgitat · completed
NCT05404100 — Effects of Aortic Valve Replacement on Myocardial T1 Values in Severe Aortic Valve Stenosis · completed
NCT04455165 — Factors Influencing Morbi-mortality in Right Anterior Minithoracotomy Approch for Aortic Valve Replacement · completed
NCT04204915 — The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study · NA · recruiting

Other recruiting trials for Aortic Valve Stenosis

Currently open trials in the same condition.

NCT07455292 — Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging · NA · recruiting
NCT07008911 — CardioHeartConnect: Commercially Available Fitness for Cardiac Rehabilitation · NA · recruiting
NCT07145463 — Prospective, Multicenter, Randomized Controlled Clinical Study Evaluating the VitaFlow Liberty® Flex Transcatheter Aorti · NA · recruiting
NCT07520656 — Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered Breathing · recruiting
NCT07267117 — Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease · recruiting

Other Turku University Hospital trials

Trials by the same sponsor.

NCT07488494 — Effective Implementation of the Physical Activity and Motor Skills Intervention for 3-6-year-old Children With Cancer (E · NA · not yet recruiting
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NCT07306000 — Pilot Study: Effects of CCP Intervention on NICU Environment and Preterm Infants Development · NA · recruiting
NCT07272824 — Usability Study of Gestational and Postpartum Weight Management Program · recruiting
NCT07310472 — Administration of the Nasal Influenza Vaccine to Children in Daycare or at a Healthcare Facility · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03385915 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Turku University Hospital
Last refreshed: 10 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03385915.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing