Last reviewed · How we verify
NCT03382860
Estimation of Intracranial Pressure Using Non-invasive Fundus Videos
trial testing Fundus videos in Intracranial Pressure in 50 participants. Status unknown.
1 August 2025
Quick facts
| Lead sponsor | Odense University Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 June 2017 |
| Primary completion | 1 August 2025 |
| Estimated completion | 1 August 2025 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Fundus videos
Conditions studied
- Intracranial Pressure — all drugs for Intracranial Pressure →
Sponsor
Odense University Hospital
Who can join
18 and older, any sex, with Intracranial Pressure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this pilot study is to assess whether the intracranial pressure (ICP) can be detected by using a non-invasive retinal fundus scanner, recording the vessels of the eye entering from the optic disc. The artery's diameter (A) is measured and compared to the vein's diameter (V) thereby a ratio A/V can be calculated. This ratio is compared to the values obtained from conventional fiberoptic intraparenchymal, intraventricular ICP monitoring using external ventricular drain (EVD) or lumbar pressure monitoring. Valid non-invasive techniques for objective measurements of the intracranial pressure do not exist at the given time now and this study could prove to help the development of monitoring patients ICP without surgical intervention.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
A new novel method for assessing intracranial pressure using non-invasive fundus images: a pilot study.
Andersen MS, Pedersen CB, Poulsen FR. · · 2020 · cited 17× · PMID 32747697 · DOI 10.1038/s41598-020-70084-0 -
The Current State of Clinical Trials Studying Hydrocephalus: An Analysis of ClinicalTrials.gov.
Abraham ME, Povolotskiy R, Gold J, Ward M, et al · · 2020 · cited 3× · PMID 32983722 · DOI 10.7759/cureus.10029
Verify or expand the search:
- PubMed search for NCT03382860
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Intracranial Pressure
Currently open trials in the same condition.
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- NCT07222826 — Non-invasive Intracranial Pressure Estimation by Measurement of the Occlusion Pressure of the Isolated Periorbital Vein · NA · recruiting
- NCT07062367 — Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cereb · NA · recruiting
- NCT06979999 — The Effects of Positive End-expiratory Pressure (PEEP) on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy · NA · recruiting
- NCT06547411 — Effects of Different Anesthesia Machine Modalities on Bariatric Surgery Patients: a Prospective Randomized Controlled St · NA · recruiting
Other Odense University Hospital trials
Trials by the same sponsor.
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- NCT07466212 — QoLIDia: Quality of Life in Cancer Patients With Diabetes During Immunotherapy · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03382860 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Odense University Hospital
- Last refreshed: 2 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03382860.
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