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NCT03379805
Lymphatic Function in Patients With a Fontan-Kreutzer Circulation
trial testing Near Infrared Fluorescence Imaging in Lymphatic Abnormalities in 10 participants. Status unknown.
20 June 2017
Quick facts
| Lead sponsor | University of Aarhus |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 10 |
| Start date | 25 April 2014 |
| Primary completion | 20 June 2017 |
| Estimated completion | 31 August 2018 |
Drugs / interventions tested
- Near Infrared Fluorescence Imaging
- Non-contrast MRI
- Strain Gauge Plethysmography
Conditions studied
- Lymphatic Abnormalities — all drugs for Lymphatic Abnormalities →
- Lymphatic Edema — all drugs for Lymphatic Edema →
- Univentricular Heart — all drugs for Univentricular Heart →
Sponsor
University of Aarhus
Who can join
18 and older, any sex, with Lymphatic Abnormalities or Lymphatic Edema. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The lymphatics regulate the interstitial fluid by removing excessive fluid. It represents an extremely important step in the prevention of edema. The Fontan-Kreutzer procedure has revolutionized the treatment of univentricular hearts. However, it is associated with severe complications such as protein-losing enteropathy (PLE) and peripheral edema that may involve the lymphatic circulation. Our hypothesis is that patients with a univentricular circulation have a reduced functionality of the lymphatic vasculature, which predisposes them to developing complications such as edema and PLE. The functional state of lymphatics is investigated using near infrared fluorescence imaging, NIRF. The anatomy is described using non-contrast MRI and the capillary filtration rate is measured using plethysmography.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Morphology and Function of the Lymphatic Vasculature in Patients With a Fontan Circulation.
Mohanakumar S, Telinius N, Kelly B, Lauridsen H, et al · · 2019 · cited 61× · PMID 30943769 · DOI 10.1161/circimaging.118.008074
Verify or expand the search:
- PubMed search for NCT03379805
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lymphatic Abnormalities
Currently open trials in the same condition.
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- NCT05731141 — A Prospective Natural History Study of Lymphatic Anomalies · recruiting
Other University of Aarhus trials
Trials by the same sponsor.
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- NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03379805 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Aarhus
- Last refreshed: 20 December 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03379805.
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